Protein Alignment Est-P and cest-5.1

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_501022.3
• Gene: cest-5.1 / 177429
• WormBaseID: WBGene00015279
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 499
• Identity: 115/499 - (23%)
• Similarity: 196/499 - (39%)
• Gaps: 99/499 - (19%)

  Fly    10 LTLLWIAALESEADPLIVEITNGKIRGKDNGLYYSYESIPNAEHPTGALRFEAPQPYSHHWTDVF 74
            |.||.:..:.:.||.||:..:.|.:.|.:.|.|:.::.||.|:.|.|.|||:.|:. :..|..:.
 Worm     4 LRLLLLIFIINAADSLIIHTSFGHLEGAEIGDYHLFKKIPFAKPPVGNLRFQKPEA-AGKWDGIR 67

  Fly    75 NATQSPVECMQWNQFINENNKLMGDEDCLTVSIYKPKKPNRS-SFPVVVLLHGGAFMFGSGSIYG 138
            :|.:....||. |....::.:...|||||.|:|:..||..:| :..:.|.:|||...:.|..::.
 Worm    68 SAIEYGPACMS-NSSKTKSPQKWVDEDCLHVNIFTSKKCLKSRNCAIAVYIHGGGLTYDSAVMFN 131

  Fly   139 H----DSIMREGTLLVVKISFGLGPLGFASTGDRHL-PGNYGLKDQRLALQWIKKNIAHFGGMPD 198
            .    |:.::...:||:. .|.||.....:..:::: |.|..|.|..|||:::|..|..|||...
 Worm   132 DTVLLDTFVKRDVILVIP-GFRLGIFSHFTVHNQNVAPNNLALYDITLALEFVKSEIHSFGGNSQ 195

  Fly   199 NIVLIGHSAGGASAHLQLLHEDFKH---LAKGAISVSGNALDPWVIQQ-----GGRRRAFELGRI 255
            .|.|.|||.||..|.:.....:...   |.:.||.:||.    :..::     .|.:|..|
 Worm   196 KITLFGHSYGGGLASMMTFSSEINRDLSLFQQAIVMSGG----FYFEELKDHIEGTKRFVE---- 252

  Fly   256 VGCGHTNVSAELK---------------DCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSD 305
                :.|.|..||               .||:.....:::...|......|..|.  |.::....
 Worm   253 ----YANCSVPLKLERKMERSQQEMYMMKCLQKLSGMELLRIQRLLEDKGYPDFG--GVILREPL 311

  Fly   306 APDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGYNAAQLLERNKLTGESWIDLLNDRWFDWAPY 370
            .||....|    ::||.|  .:|.....|..:..:.:.::                    .:..|
 Worm   312 FPDVKKFE----LLKSPK--NIPMLTGCTNLEFDHESIKV--------------------PFGKY 350

  Fly   371 LLFYRDAKKTIKDMDDLSFDLRQQYLADRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRKYGKS 435
            |.|        ::.|:..    ::|..|....||:..|    .||......:|..:.::.....:
 Worm   351 LEF--------ENPDECD----EKYRNDVESGVENRGN----HTDKTQGIILPLKLQINNLLENN 399

  Fly   436 -PVYSFVYDNP-----TDS-----GVGQLLSNRTDVHFGTVHGD 468
             ..|.:.|..|     ||.     ||.....:..:||...|:.|
 Worm   400 VTAYLYEYTYPKHGRHTDDLSYIMGVHAFEKDENEVHLEQVYKD 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	109/483 (23%)
		Aes	<107..>240	CDD:223730	40/141 (28%)
cest-5.1	NP_501022.3	Abhydrolase	19..495	CDD:389770	110/484 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156871
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740