Protein Alignment Est-P and ace-3

DIOPT Version :10

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_496963.1
• Gene: ace-3 / 175076
• WormBaseID: WBGene00000037
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 621
• Identity: 157/621 - (25%)
• Similarity: 261/621 - (42%)
• Gaps: 131/621 - (21%)

  Fly     5 KRLLCL-----TLLWIA-ALESEADPLIVEITN--GKIRGKD----NGLYYSYESIPNAEHPTGA 57
            :|:|.|     |.|.:: |.:.|....:||:..  |.:||.:    |....|:..:|.||.|...
 Worm     4 RRVLLLLLSTTTFLRVSTAQQDEPKASVVEVQTKLGTVRGTESDHGNKRVRSFLGVPFAEPPINE 68

  Fly    58 LRFEAPQPYSHHWTDVFNA-TQSPVECMQ---------W-NQFINENNKLMGDEDCLTVSIYKPK 111
            .||:.|.| :..|....:| |.||. |.|         | ::..|.|..:  .||||.|:|:.|
 Worm    69 HRFKKPTP-ARPWNGTISANTLSPA-CFQGRDSYDPTFWGSEMWNANTPV--SEDCLYVNIWAP- 128

  Fly   112 KPNRSSFPVVVLLHGGAFMFGSGS--IYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPGNY 174
             .:..:..|:|.|.||.|.:||.|  :|....:...|.::||.|::.:||.|:.......:|||.
 Worm   129 -ADAYNLTVLVWLFGGGFWYGSPSLLLYDGKELATRGNVIVVNINYRVGPFGYLFLDHEDVPGNM 192

  Fly   175 GLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPW 239
            |:.||:|||.||:.:|..|||.|..|.|:|.|||.||....|:....|.|.:..|..||:..:.|
 Worm   193 GMLDQQLALYWIRDHIFSFGGNPARISLVGESAGAASIVAHLIAPASKGLFQNGILQSGSLDNKW 257

  Fly   240 VIQ--QGGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAV----RSFLVFSYVPFSAFG 298
            .:.  :..::::..|..:|||..|.::.:.. ||::.||..::..:    .:||.|   ||:..
 Worm   258 SMDSPKRAKQKSTALADLVGCNQTKITDQTA-CLRNTPAQLLIDNIWNVGLNFLEF---PFAIV- 317

  Fly   299 PVVEPSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTE---------DGG-----YNAAQLLERN 349
                 |...:.|...|....::.|         ||:|:         |.|     ||.|:..::.
 Worm   318 -----SKDQNFFKHLDGFIALREG---------TYSTDVNLMFGINHDEGNFWNIYNLAKFFDKQ 368

  Fly   350 K----LTGESWIDLLNDRWFDWAPYLL------FYRDAKKT-IKDMDDLSFDLRQQYLADRRFSV 403
            .    |..:.:.:.: |..|...|.|:      .|.|.|.| .|...|...:...|.:.|..|:.
 Worm   369 SVKPGLDRDEFHECV-DTAFAVQPELVRTAAKYVYSDPKCTDPKKKTDFYTEQVNQMVGDYFFTC 432

  Fly   404 ESYWNVQRMFTDVLFKNSVPSAIDLHRKYGKSPVYSFVYDNPTDSGVGQLLSNRTDVHFGTVHGD 468
            :|.|          |.::.|....     .:|.|:.:.:|.|:.       :|......|.:||.
 Worm   433 DSIW----------FAHNYPKMAG-----NQSNVFVYYFDQPSS-------ANPWPKWTGVMHGY 475

  Fly   469 DFFLIFNTAAYRT--GIRPDEEVISKKFIGMLEDFA------LNDKGTLTFGECNFQN------- 518
            :...:|....:.|  |...:|..:|:|.|.....||      |..:...|..:..:..
 Worm   476 EIEYVFGVPLHNTTAGYTKEEMDVSEKVIDFWTTFANTGVPSLRKRAVGTTQKIKWDRYDGTDHT 540

  Fly   519 ---NVNSKEYQVLR--------ISRNACKNEEYARF 543
               |:.:..:::::        :.||| |:.||:.:
 Worm   541 TWMNIKTGSFRMIQEIKKVECDLWRNA-KDMEYSAY 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	147/586 (25%)
ace-3	NP_496963.1	COesterase	33..564	CDD:395084	143/578 (25%)