Protein Alignment Est-P and ace-4

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_496962.1
• Gene: ace-4 / 175074
• WormBaseID: WBGene00000038
• Length: 602
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 158/603 - (26%)
• Similarity: 240/603 - (39%)
• Gaps: 134/603 - (22%)

  Fly    24 PLIVEITNGKIRGKDNGLYY------SYESIPNAEHPTGALRFEAPQPYSHHWTDVFNATQSPVE 82
            |:::|...|.|:|.:  .::      ::..:|.||......||..|:. ...|..:::||:....
 Worm    26 PVVLETKLGDIKGTE--FFFLSKKIRTFFGVPFAEPAVEDFRFRKPRE-KKQWRGLYDATKPANA 87

  Fly    83 CMQ---------W-NQFINENNKLMGDEDCLTVSIYKPKKPNRSSFPVVVLLHGGAFMFGSG--S 135
            |.|         | ::..|.|.::  .||||.::|:.|  .:..:..|:|...||.|..||.  |
 Worm    88 CFQTRDNYNTSFWGSEMWNANTQI--SEDCLYLNIWAP--ADAYNLTVMVWFFGGGFYSGSPSLS 148

  Fly   136 IYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPGNYGLKDQRLALQWIKKNIAHFGGMPDNI 200
            ||...::.....::||.|::.|||.||...|....|||.||.||:|||.|:::||..|||.||.:
 Worm   149 IYDGKALTSTQNVIVVNINYRLGPFGFLYLGHPDAPGNMGLLDQQLALHWVRQNIVSFGGNPDKV 213

  Fly   201 VLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQ--GGRRRAFELGRIVGCGHTNV 263
            .:.|.|||.||....|:....:.|.|.||..||:..:.|.|..  ..::::.:|..:|||..|.|
 Worm   214 AVFGQSAGAASIVAHLIAPGSRGLFKNAILQSGSLENTWAINSPFRAKQKSEKLLELVGCNKTTV 278

  Fly   264 SAELKDCLKSKPASDIVSAVRSFL-----VFSYVPFSAFGPVVEPSDAPDAFLTEDPRAVIKSGK 323
            ...:. ||:      :||..:..|     ..:|:.|    |.|..|.....|...|..|.::.|.
 Worm   279 DTSMA-CLR------LVSPEQLSLSTWNISLTYLEF----PFVIVSRDKHFFGHLDAHAALREGD 332

  Fly   324 F-AQVPWAVTYTTEDGGY-NAAQL-----------LERNKLTGESWIDLLNDRWFDWAPYLLFYR 375
            | ..|...:....::|.| |..||           |.|.:      .|.|.||.|...|.::  |
 Worm   333 FNRDVNLMIGMNKDEGNYWNIYQLPQFFDKADPPELNRTE------FDFLIDRTFSIQPDII--R 389

  Fly   376 DAKKTIKDMDDLSFDLRQ---------QYLADRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRK 431
            .|.|.|....:.:...|:         |.:.|..||.:|.|...:..:....|:|.|     .||
 Worm   390 SAAKYIYSDPNCTDHGRKTRFYAGQMNQIVGDYFFSCDSLWLADQFRSIPRVKSSSP-----QRK 449

  Fly   432 YGKSPVYSFVYDNPTDSGVGQLLSNRTDVHFGTVHGDDFFLIFN-TAAYRTGIRPDEEVISKKFI 495
            .||..||.|...:.         :|......|.:||.:...:|. ..:|....:..|::.|:|.:
 Worm   450 PGKVFVYHFTQSSS---------ANPWPKWTGAMHGYEIEYVFGIPLSYSKNYKRREQIFSRKIM 505

  Fly   496 GMLEDFALNDKGT-------------------------LTFG------------ECNFQNNVNSK 523
            .....||.|  ||                         |..|            ||.|...|...
 Worm   506 QFWASFAKN--GTPKLRVLKNSEHWPEFNEQNHYRWMQLRSGSNIRPIKPKKQVECQFWRRVKDT 568

  Fly   524 EYQVLRISRNACKNEEYA 541
            ||       .|...:||:
 Worm   569 EY-------TAYLTQEYS 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	155/595 (26%)
		Aes	<107..>240	CDD:223730	52/134 (39%)
ace-4	NP_496962.1	COesterase	28..562	CDD:278561	150/575 (26%)
		Aes	<120..>243	CDD:223730	49/124 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156955
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840