Protein Alignment Est-P and ace-2

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_491141.1
• Gene: ace-2 / 171905
• WormBaseID: WBGene00000036
• Length: 629
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 140/599 - (23%)
• Similarity: 221/599 - (36%)
• Gaps: 179/599 - (29%)

  Fly     3 IFKRLLCLTLLWIAALESEA---DPLIVEITNGKIRGK----DNGLYYSYESIPNAEHPTGALRF 60
            :|.:...:||..:..:|..:   ...:|....|.|||.    |.....::..:|.|:.|.|:.||
 Worm    14 VFCQFALVTLFIVRRIEPRSIVRGDHVVHTPLGTIRGVGQTFDGAKVSAFLGVPYAKPPIGSRRF 78

  Fly    61 EAPQPYSHHWTDVFNATQSPVECM--------------QWNQFINENNKLMG--DEDCLTVSIYK 109
            :..:... .|:....|......|.              .||.        .|  .||||.::|:.
 Worm    79 KMAEMID-RWSGELEARTLAKTCYLTIDSAFPQFPGAEMWNP--------PGAISEDCLNMNIWV 134

  Fly   110 PKKPNRSSFPVVVLLHGGAFMFG-------SGSIYGHDSIMREGTLLVVKISFGLGPLGFASTG- 166
            |:..:.|   |:|.::||.|..|       |||::.    .:|.| :||.:::.|||.||...|
 Worm   135 PEDHDGS---VMVWIYGGGFFSGTPSLDLYSGSVFA----AKEHT-IVVNVNYRLGPFGFLYFGD 191

  Fly   167 DRHLPGNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLL----HEDFKHLAKG 227
            |..:.||.||.||:|||:|:.:||..|||....:.|.|.|||.||....|.    |:.|:::
 Worm   192 DSPIQGNMGLMDQQLALRWVHENIGAFGGDRSRVTLFGESAGSASTTAHLFAPNSHKYFRNI--- 253

  Fly   228 AISVSGNALDPWVIQQGGRR--RAFELGRIVGCGHTNVSAELKDCLKSKPA------SDIVSA-V 283
             |:.||:.::.|........  .:|.|.:.|.|...:::|.:| ||:|.||      :|.:|. :
 Worm   254 -IAKSGSIINSWASATPPTMLDLSFRLAKKVNCSSPDMNAIVK-CLRSVPAHLVQAEADNISGDI 316

  Fly   284 RSFLVFSYVPFSAFGPVVEPSDA----PDAF-------LTEDPRAVIKSGKFAQVPWAVTYTTED 337
            ...:.|:|||.|        |||    .|.|       ..:|...:..|.|            ::
 Worm   317 GPPMTFAYVPVS--------SDANFFQGDVFQKLANKQFKKDVNIIFGSVK------------DE 361

  Fly   338 GGYNAAQLLERNKLTGESWIDLLNDRWFDWAPYLLFYRDAKK-------TI------------KD 383
            |.|                          |.||   |....|       ||            :|
 Worm   362 GTY--------------------------WLPY---YMSLPKYGFAFNHTISAEDPHNRALITRD 397

  Fly   384 MDDLSFDLRQQYLADRRFSVESYWN------------------VQRMFTDVLFKNSVPSAIDL-- 428
            ..:.|......|.|..:..:.::.|                  |.|...|:.|..|:....||
 Worm   398 HYEESMRAFMPYFAGSKLVLNAFMNSYEHVSTSNVPEERYRDGVARFLGDLFFTCSLIDFADLIS 462

  Fly   429 HRKYGKSPVYSFVYDNPTDSGVGQLLSNRTDVHFGTVHGDDFFLIFNTAAYRTGI-----RPDEE 488
            ...:|...:|.|.|.:.         :|......|.:||.:....|....:|..:     ..||:
 Worm   463 DNIFGNVYMYYFTYRSS---------ANPWPKWMGVMHGYEIEYAFGQPYWRPHLYDQTHLEDEK 518

  Fly   489 VISKKFIGMLEDFA 502
            .:|...:.:..:||
 Worm   519 RLSSIIMQIWANFA 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	136/573 (24%)
		Aes	<107..>240	CDD:223730	51/144 (35%)
ace-2	NP_491141.1	COesterase	33..546	CDD:278561	136/580 (23%)
		Aes	<135..>233	CDD:223730	40/105 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910