Protein Alignment Est-P and Nlgn3

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_599163.2
• Gene: Nlgn3 / 171297
• RGDID: 621119
• Length: 848
• Species: Rattus norvegicus
• Alignment Length: 607
• Identity: 156/607 - (25%)
• Similarity: 240/607 - (39%)
• Gaps: 170/607 - (28%)

  Fly     6 RLLCLTLLWIAAL----ESEADPLIVEITNGKIRG-------KDNGLYYSYESIPNAEHPTGALR 59
            |.||| :||..:|    .::|....|....||:||       :..|....|..:|.|..|.|..|
  Rat    20 RSLCL-ILWFLSLVLRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKR 83

  Fly    60 FEAPQPYSHHWTDVFNATQSPVECMQ-------------W--------NQFINENNKLMGDEDCL 103
            |..|:| ...|:.:.|||..|..|.|             |        ..:|.|.|     ||||
  Rat    84 FLPPEP-PPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPN-----EDCL 142

  Fly   104 TVSIYKP------------KKPNR-------------------------------SSFPVVVLLH 125
            .:::|.|            :|||:                               .:.||:|.:|
  Rat   143 YLNVYVPTEDVKRISKECARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIH 207

  Fly   126 GGAFMFGSGSIYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPGNYGLKDQRLALQWIKKNI 190
            ||::|.|:|::.....:...|.::|:.:::.:|.|||.||||:...|||||.||..||:|:.:||
  Rat   208 GGSYMEGTGNMIDGSVLASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENI 272

  Fly   191 AHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQGGRRRAFELGRI 255
            |.|||.|..|.:.|...|.:...|..|....:.|.:.||..||:||..|.:.....:....|...
  Rat   273 AFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADK 337

  Fly   256 VGCGHTNV--SAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAPDAFLTEDPRAV 318
            |||   ||  :.::.|||:.|.|.::|.  :......|  ..|||||::....||     ||..:
  Rat   338 VGC---NVLDTVDMVDCLRQKSAKELVE--QDIQPARY--HVAFGPVIDGDVIPD-----DPEIL 390

  Fly   319 IKSGKFAQVPWAVTYTTEDGGYNAAQLLERNKLTGESWI-------DLLNDRWFDWA-----PYL 371
            ::.|:|               .|...:|..|:..|..::       |.::...||::     ..|
  Rat   391 MEQGEF---------------LNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNL 440

  Fly   372 LFYRDAKKTIKDMDDLSFDLRQQYL--ADRRFSVESYWNVQRMFTDVLFKNSVPSAI--DLHRKY 432
            ..|.:.|.|:::      .::..|.  |||.........:..:|||..:..  ||.:  |||.:|
  Rat   441 YGYPEGKDTLRE------TIKFMYTDWADRDNPETRRKTLVALFTDHQWVE--PSVVTADLHARY 497

  Fly   433 GKSPVYSFVYDNPTDSGVGQLLSNRTDVHFGTVHGDDFFLIFNTAAYRTGIRPDEEVISKKFIGM 497
            | ||.|.:.:.:...|.:....|:       ..|||:...:|..                ..:|.
  Rat   498 G-SPTYFYAFYHHCQSLMKPAWSD-------AAHGDEVPYVFGV----------------PMVGP 538

  Fly   498 LEDFALNDKGTLTFGECNFQNN 519
            .:.|           .|||..|
  Rat   539 TDLF-----------PCNFSKN 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	148/583 (25%)
		Aes	<107..>240	CDD:223730	53/175 (30%)
Nlgn3	NP_599163.2	COesterase	40..624	CDD:395084	148/586 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..195		0/25 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..691

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336082
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.830