Protein Alignment Est-P and AADACL3

DIOPT Version :10

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001096640.2
• Gene: AADACL3 / 126767
• HGNCID: 32037
• Length: 407
• Species: Homo sapiens
• Alignment Length: 117
• Identity: 31/117 - (26%)
• Similarity: 51/117 - (43%)
• Gaps: 21/117 - (17%)

  Fly   103 LTVSIYKPKKPNRSSFPVVVLLHGGAFMFGSGSIYGHDSI----MREGTLLVVKISFGLGPLGFA 163
            :.|.:|:||....:..|.:|..|||..:.  ||:..|..|    .:|...:|:.:
Human    97 IPVKLYQPKASTCTLKPGIVYYHGGGGVM--GSLKTHHGICSRLCKESDSVVLAV---------- 149

  Fly   164 STGDRHLPGN---YGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASA 212
              |.|.||.:   ..::|..:|.....|::..:|..|..:|:.|.|.|||.|
Human   150 --GYRKLPKHKFPVPVRDCLVATIHFLKSLDAYGVDPARVVVCGDSFGGAIA 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	31/117 (26%)
AADACL3	NP_001096640.2	Abhydrolase_3	115..378	CDD:400284	26/99 (26%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	119..121		1/1 (100%)