Protein Alignment Est-P and Ces1g

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_067431.2
• Gene: Ces1g / 12623
• MGIID: 88378
• Length: 565
• Species: Mus musculus
• Alignment Length: 599
• Identity: 155/599 - (25%)
• Similarity: 240/599 - (40%)
• Gaps: 130/599 - (21%)

  Fly     7 LLCLTLLWIAA---LESEADPLIVEITNGKIRGKDNGLYYSYE----------SIPNAEHPTGAL 58
            |..|:|:.:.|   |...:.|.:|...:||:.||    |.:.|          .:|.|:.|.|:|
Mouse     3 LCALSLISLTACLSLGHPSLPPVVHTVHGKVLGK----YVTLEGFSQPVAVFLGVPFAKPPLGSL 63

  Fly    59 RFEAPQPYSHHWTDVFNATQSPVECMQWNQ--------FINENNKLMG---DEDCLTVSIYKPKK 112
            ||..|:| :..|:.|.:.|..|..|.|..:        |.|: .|::.   .||||.::||.|..
Mouse    64 RFAPPEP-AEPWSFVKHTTSYPPLCYQNPEAALRLAELFTNQ-RKIIPHKFSEDCLYLNIYTPAD 126

  Fly   113 PNRSS-FPVVVLLHGGAFMFGSGSIYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPGNYGL 176
            ..::| .||:|.:|||..:....|.|....:.....::||.|.:.||..||.||.|.|..||:|.
Mouse   127 LTQNSRLPVMVWIHGGGLVIDGASTYDGVPLAVHENVVVVVIQYRLGIWGFFSTEDEHSRGNWGH 191

  Fly   177 KDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVI 241
            .||..||.|::.|||:|||.|.::.:.|.||||.|..:.:|....|:|...||:.|....:|.:.
Mouse   192 LDQVAALHWVQDNIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAIAQSSVIFNPCLF 256

  Fly   242 QQGGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVE---- 302
            .:..|..|.::..:.|| .|..||.:..||:.|...:::. |...:.|..|.|  .|...|
Mouse   257 GRAARPLAKKIAALAGC-KTTTSAAMVHCLRQKTEDELLE-VSLKMKFGTVDF--LGDPRESYPF 317

  Fly   303 -PSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGYNAAQLLE----RNKLTGESWIDLLND 362
             |:......|.:.|..::....|..||:.|.....:.|:.....|:    ..||..::...:|
Mouse   318 LPTVIDGVLLPKAPEEILAEKSFNTVPYMVGINKHEFGWIIPMFLDFPLSERKLDQKTAASIL-- 380

  Fly   363 RWFDWAPYLLF-------------YRDAKKTIKDMDDLSFDLRQQYLADRRFSVESYWNVQRMFT 414
                |..|.:.             |....:....|.||..||                     ..
Mouse   381 ----WQAYPILNISEKLIPAAIEKYLGGTEDPATMTDLFLDL---------------------IG 420

  Fly   415 DVLFKNSVPSAI--DLHRKYGKSPVYSFVYD-NP---TDSGVGQLLSNRTDVHFGTVHGDDFFLI 473
            |::|  .|||.|  ..||..| :|.|.:.|. .|   :|....:||.:         |.|:.|.:
Mouse   421 DIMF--GVPSVIVSRSHRDAG-APTYMYEYQYRPSFVSDDRPQELLGD---------HADELFSV 473

  Fly   474 FNTAAYRTGIRPDEEVISKKFIGMLEDFALN----------------DKGTLTFG---------- 512
            :.....:.|...:|..:||..:....:||.|                .:|.|..|
Mouse   474 WGAPFLKEGASEEEINLSKMVMKFWANFARNGNPNGEGLPHWPEYDQKEGYLQIGVPAQAAHRLK 538

  Fly   513 --ECNFQNNVNSKE 524
              |.:|...:.:||
Mouse   539 DKEVDFWTELRAKE 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	149/577 (26%)
		Aes	<107..>240	CDD:223730	51/133 (38%)
Ces1g	NP_067431.2	COesterase	24..545	CDD:278561	146/569 (26%)
		Aes	<121..>239	CDD:223730	46/117 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832543
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840