Protein Alignment Est-P and Bche

DIOPT Version :10

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001415300.1
• Gene: Bche / 12038
• MGIID: 894278
• Length: 615
• Species: Mus musculus
• Alignment Length: 589
• Identity: 161/589 - (27%)
• Similarity: 250/589 - (42%)
• Gaps: 118/589 - (20%)

  Fly    12 LLWIAAL-------ESEADPLIVEITNGKIRGKD----NGLYYSYESIPNAEHPTGALRFEAPQP 65
            ||||..|       .:|.| .|:....|::||..    .|...::..||.|:.|.|:|||:.|||
Mouse    26 LLWILLLCMPFGKSHTEED-FIITTKTGRVRGLSMPVLGGTVTAFLGIPYAQPPLGSLRFKKPQP 89

  Fly    66 YSHHWTDVFNATQSPVEC----------MQWNQFINENNKLMGDEDCLTVSIYKP-KKPNRSSFP 119
            . :.|.|:.||||....|          .|.::..|.|..|  .||||.::::.| .||..::
Mouse    90 L-NKWPDIHNATQYANSCYQNIDQAFPGFQGSEMWNPNTNL--SEDCLYLNVWIPVPKPKNAT-- 149

  Fly   120 VVVLLHGGAFMFGSGS--IYGHDSIMREGTLLVVKISFGLGPLGF-ASTGDRHLPGNYGLKDQRL 181
            |:|.::||.|..|:.|  :|....:.|...::||.:::.:|.||| |..|:...|||.||.||:|
Mouse   150 VMVWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALGFLAFPGNPDAPGNMGLFDQQL 214

  Fly   182 ALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQ--QG 244
            ||||:::|||.|||.|.:|.:.|.|||.||..|.||......|...||..||::..||.::  :.
Mouse   215 ALQWVQRNIAAFGGNPKSITIFGESAGAASVSLHLLCPQSYPLFTRAILESGSSNAPWAVKHPEE 279

  Fly   245 GRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAPDA 309
            .|.|...|.:..||...| ..|:..||:||...:|:...|..|....:....|||.|:..
Mouse   280 ARNRTLTLAKFTGCSKEN-EMEMIKCLRSKDPQEILRNERFVLPSDSILSINFGPTVDGD----- 338

  Fly   310 FLTEDPRAVIKSGKFAQVPWAVTYTTEDGG----YNAAQLLERNK--LTGESWIDLLN------D 362
            |||:.|..:::.||..:....|....::|.    |.|....:.|.  :|.:.:.:.||      .
Mouse   339 FLTDMPHTLLQLGKVKKAQILVGVNKDEGTAFLVYGAPGFSKDNDSLITRKEFQEGLNMYFPGVS 403

  Fly   363 R---------WFDW----APYLLFYRDAKKTIKDMDDLSFDLRQQYLADRRFSVESYWNVQRMFT 414
            |         :.||    :|.:  ||||      :||:..|.
Mouse   404 RLGKEAVLFYYVDWLGEQSPEV--YRDA------LDDVIGDY----------------------- 437

  Fly   415 DVLFKNSVPSAIDLHRKYGKSPVYSFVYDNPTDSGVGQLLSNRTD-----VHFGTVHGDDFFLIF 474
                 |.:..|::..:|:.:....:|.|          ...:|:.     ...|.:||.:...:|
Mouse   438 -----NIICPALEFTKKFAELENNAFFY----------FFEHRSSKLPWPEWMGVMHGYEIEFVF 487

  Fly   475 N-TAAYRTGIRPDEEVISKKFIGMLEDFALNDKGTLTFGECNFQNNVNSKEYQVLRISRNACKNE 538
            . ....|......||:.|:..:....:||.......|.|.........|.|.:.|.:  |..|::
Mouse   488 GLPLGRRVNYTRAEEIFSRSIMKTWANFAKYGHPNGTQGNSTMWPVFTSTEQKYLTL--NTEKSK 550

  Fly   539 EYAR 542
            .|::
Mouse   551 IYSK 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	152/561 (27%)
Bche	NP_001415300.1	COesterase	43..563	CDD:395084	155/572 (27%)
		AChE_tetra	578..612	CDD:430146