Protein Alignment Est-P and ache

DIOPT Version :10

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_571921.1
• Gene: ache / 114549
• ZFINID: ZDB-GENE-010906-1
• Length: 634
• Species: Danio rerio
• Alignment Length: 552
• Identity: 150/552 - (27%)
• Similarity: 245/552 - (44%)
• Gaps: 91/552 - (16%)

  Fly    20 SEADP-LIVEITNGKIRG-----KDNGLYYSYESIPNAEHPTGALRFEAPQPYSHHWTDVFNATQ 78
            ::|:| |:|....|:::|     .|.....::..||.||.|.|..||:..:| ...|.:||.|.:
Zfish    23 AQAEPDLVVATRLGRVQGTRLPVPDRSHVIAFLGIPYAEPPIGKRRFKRAEP-KKPWNNVFEAKE 86

  Fly    79 SPVECMQ--------------WNQFINENNKLMGDEDCLTVSIYKPKKPNRSSFPVVVLLHGGAF 129
            ....|.|              ||.     |::| .||||.::::.|..|...:..|:|.::||.|
Zfish    87 FSNACYQFVDTSYPGFPGIEMWNP-----NRVM-SEDCLYLNVWVPPTPRPQNLTVMVWIYGGGF 145

  Fly   130 MFGSGSIYGHDS--IMREGTLLVVKISFGLGPLGF-ASTGDRHLPGNYGLKDQRLALQWIKKNIA 191
            ..||.|:..:|.  :.....::||.:::.:|..|| |..|....|||.||.||||||||:::||.
Zfish   146 YSGSSSLDVYDGRYLAYTEKVVVVSMNYRVGAFGFLALNGSSDAPGNVGLYDQRLALQWVQENIH 210

  Fly   192 HFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPW--VIQQGGRRRAFELGR 254
            .|||.|..:.:.|.|||.||..:.:|..|.:.|...||..||....||  |.....|||..:||:
Zfish   211 FFGGNPKQVTIFGESAGAASVGMHVLSPDSRPLFTRAILQSGVPNTPWATVTFDEARRRTTKLGK 275

  Fly   255 IVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAPDAFLTEDPRAVI 319
            :|||...| ..||.|||::|...:::......|.:|.:...:|.|||:     ..|..:.|.|:|
Zfish   276 LVGCTWGN-DTELIDCLRNKHPQELIDQEWQVLPWSSLFRFSFVPVVD-----GVFFPDTPDAMI 334

  Fly   320 KSGKFAQVPWAVTYTTEDGG----YNAAQLLERNK--LTGESWIDLL-------ND--------R 363
            .||.|......:....::|.    |.|....:.|:  ::.|.:::.:       ||        :
Zfish   335 SSGNFKYTQILLGVNQDEGSYFLLYGAPGFSKDNESLISREDFLESVKMGVPHANDIGLEAVILQ 399

  Fly   364 WFDWAPYLLFYRDAKKTIKDMDDLSFDLRQQYLADRRFSVESYWNVQRMFTD--------VLFKN 420
            :.||    :...:.:|....|||:..|  |..:...:...:||.....:...        :.:.|
Zfish   400 YTDW----MDENNGQKNRDAMDDIVGD--QNVICPLQHFAKSYAQYAALHAQSSAAAPGTLGWGN 458

  Fly   421 SVPSAIDLHRKYGKSPVYSFVYDNPTDSGVGQLLSNRT-DVHFGTVHGDDFFLIFN-TAAYRTGI 483
            |.|:..:....:|  .||.:::|:..        ||.. ....|.:||.:...:|. ....|...
Zfish   459 SGPTGYNSGNSHG--AVYLYLFDHRA--------SNLAWPEWMGVIHGYEIEFVFGLPLEKRLNY 513

  Fly   484 RPDEEVISKKFIGMLEDFA------LNDKGTL 509
            ..:||.:|::.:....:||      :|..||:
Zfish   514 TAEEEKLSRRIMRYWANFARTGNPNVNTDGTM 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	147/545 (27%)
ache	NP_571921.1	COesterase	27..583	CDD:395084	149/548 (27%)
		AChE_tetra	598..631	CDD:430146