Protein Alignment Est-P and Ache

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_036020624.1
• Gene: Ache / 11423
• MGIID: 87876
• Length: 616
• Species: Mus musculus
• Alignment Length: 560
• Identity: 156/560 - (27%)
• Similarity: 241/560 - (43%)
• Gaps: 129/560 - (23%)

  Fly     8 LCLTLLWIAA-LESEADP-LIVEITNGKIRG----KDNGLYYSYESIPNAEHPTGALRFEAPQPY 66
            |.|:||...| .|...|| |:|.:..|::||    ...|...::..||.||.|.|:.||..|:|
Mouse    20 LLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEP- 83

  Fly    67 SHHWTDVFNATQSPVECMQW----------NQFINENNKLMGDEDCLTVSIYKPKKPNRSSFPVV 121
            ...|:.|.:||.....|.|:          .:..|.|.:|  .||||.::::.|.....|..||:
Mouse    84 KRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNREL--SEDCLYLNVWTPYPRPASPTPVL 146

  Fly   122 VLLHGGAFMFGSGSIYGHDS---IMREGTLLVVKISFGLGPLGF-ASTGDRHLPGNYGLKDQRLA 182
            :.::||.|..|:.|:..:|.   ...||.:| |.:::.:|..|| |..|.|..|||.||.|||||
Mouse   147 IWIYGGGFYSGAASLDVYDGRFLAQVEGAVL-VSMNYRVGTFGFLALPGSREAPGNVGLLDQRLA 210

  Fly   183 LQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQGG-- 245
            |||:::|||.|||.|.::.|.|.|||.||..:.:|....:.|...|:..||....||.....|
Mouse   211 LQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEA 275

  Fly   246 RRRAFELGRIVGC---GHTNVSAELKDCLKSKPASDIVS------AVRSFLVFSYVPFSAFGPVV 301
            ||||..|.|:|||   |......||..||:::||.|:|.      ...|...||:|      |||
Mouse   276 RRRATLLARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFV------PVV 334

  Fly   302 EPSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGYNAAQLLERNKLTGESWIDLLNDRWFD 366
            :..     ||::.|.|:|.:|.|..:...|....::|.|
Mouse   335 DGD-----FLSDTPEALINTGDFQDLQVLVGVVKDEGSY-------------------------- 368

  Fly   367 WAPYLL-----FYRDAKKTIKDMDDLSFDLRQQYLADRRFSVESYWN-----VQRMFTDVL---- 417
               :|:     |.:|.:..|.         |.|:||..|..|....:     |...:||.|
Mouse   369 ---FLVYGVPGFSKDNESLIS---------RAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPED 421

  Fly   418 ---FKNSVPSAIDLH-------RKYGK-----SPVYSFVYDNPTDSGVGQLLSNRTDVHFGTVHG 467
               .::::.:.:..|       :..|:     :.||::::::...:....|       ..|..||
Mouse   422 PTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPL-------WMGVPHG 479

  Fly   468 DDFFLIFN-----TAAYRTGIRPDEEVISKKFIGMLEDFA 502
            .:...||.     :..|.|    :|.:.:::.:....:||
Mouse   480 YEIEFIFGLPLDPSLNYTT----EERIFAQRLMKYWTNFA 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	147/540 (27%)
		Aes	<107..>240	CDD:223730	53/136 (39%)
Ache	XP_036020624.1	COesterase	37..563	CDD:395084	149/543 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832783
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840