Protein Alignment Est-P and Ces2

DIOPT Version :10

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001177298.1
• Gene: Ces2 / 100910144
• RGDID: 6504334
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 148/545 - (27%)
• Similarity: 247/545 - (45%)
• Gaps: 85/545 - (15%)

  Fly     8 LCLTLLWIAALES-EADPLIVEITNGKIRGKDNGL------YYSYESIPNAEHPTGALRFEAPQP 65
            |.|.|:.:...:| |:.|:....| |:::||.:.:      .:::..||.|:.|.|.|||..|:|
  Rat    17 LLLLLIHVQGQDSPESSPIRTTHT-GQVQGKLDHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEP 80

  Fly    66 YSHHWTDVFNATQSPVECMQWNQFINE---------NNKLMGDEDCLTVSIYKPKKPNR-SSFPV 120
             ...|:.|.:||..|..|:|....::|         .:.:...||||.:::|.|..... |:.||
  Rat    81 -PEPWSGVRDATSQPAMCLQNLDILDEVGLLDMKMILSSISMSEDCLYLNVYAPAHAREGSNLPV 144

  Fly   121 VVLLHGGAFMFGSGSIYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPGNYGLKDQRLALQW 185
            :|.:||||.:.|..|:|....:.....|:||.|.:.||.|||.||||.|..||:|..||..||:|
  Rat   145 MVWIHGGALVVGMASMYDGSLLTVNEDLVVVTIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRW 209

  Fly   186 IKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQGGRRRAF 250
            :::|||||||.|:.:.:.|.||||.|....::....:.|..|||..||.||.|.:|.:.....:.
  Rat   210 VQQNIAHFGGNPNRVTIFGESAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVST 274

  Fly   251 ELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAPDAFLTEDP 315
            .:.::.||...: |..|..||::|..::|:...:   ||..:|....|          .||...|
  Rat   275 TVAKLSGCEAMD-SEALVRCLRAKSGAEILVINK---VFKMIPAVVDG----------EFLPRHP 325

  Fly   316 RAVIKSGKFAQVPWAVTYTTEDGGY--------NAAQLLERNKLTGESWIDLLNDRWFDWAPYLL 372
            :.::.|..|..||..:...|::  |        ..||:::  :|:.|:...:|.|.    |..::
  Rat   326 KELLASEDFHPVPSIIGVNTDE--YCCTIPMVMGTAQIIK--ELSRENLQAVLKDT----AAQMM 382

  Fly   373 FYRDAKKTIKDMDDLSFDLRQQYLADRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRKYGKSPV 437
            .       ..:..||   |.::|:.:...|.........|..|.||  .:|:....|.:...:||
  Rat   383 L-------PPECGDL---LMEEYMGNTDDSQTLQIQYTEMMGDFLF--VIPALQVAHFQRSHAPV 435

  Fly   438 YSFVYDNPTDSGVGQLLSNRTDVHFGTVHGDDFFLIFNTAAYRTGIRPD----EEVISKKFIGML 498
            |.:.:.:     ......|....|....|.|:...:|  .::.:|::.|    |.::|::.:...
  Rat   436 YFYEFQH-----APSYFKNVRPPHVKADHADEVPFVF--GSFFSGMKLDFTEEERLLSRRMMKYW 493

  Fly   499 EDFALNDKGTLTFGECNFQNNVNSK 523
            .:||.             |.|.||:
  Rat   494 ANFAR-------------QGNPNSE 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	142/526 (27%)
Ces2	NP_001177298.1	COesterase	32..540	CDD:395084	143/530 (27%)