DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Est-P and bchel

DIOPT Version :9

Sequence 1:	NP_788501.1	Gene:	Est-P / 39393	FlyBaseID:	FBgn0000594	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	XP_002937472.3	Gene:	bchel / 100135377	XenbaseID:	XB-GENE-5842192	Length:	559	Species:	Xenopus tropicalis

Alignment Length:	577	Identity:	150/577 - (25%)
Similarity:	244/577 - (42%)	Gaps:	112/577 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LCLTLLWIAALESEA-DPLIVEITNGKIRGKD----NGLYYSYESIPNAEHPTGALRF---EAPQ 64
            :|..|:....|.:.| ...|||:..||:.|.:    :|...:|..||..|.|||.|||   |..:
Frog    14 VCNLLMSFLILSTNAGHENIVEVKQGKVSGINLSVKSGYVTAYLGIPYGEPPTGRLRFKKTEQRK 78

  Fly    65 PYSHHWTDVFNATQSPVECMQ--WNQFIN--------ENNKLMGDEDCLTVSIY-KPKKPNRSSF 118
            |    |..|..|.:....|.|  .|:|..        .||::  .||||.:::: .|.||..:.
Frog    79 P----WHGVLKADKFGKSCFQNRENKFAEFPGTEMFLVNNEM--SEDCLHLNVWVPPSKPKDAH- 136

  Fly   119 PVVVLLHGGAFMFGSGS--IYGHDSIMREGTLLVVKISFGLGPLGF-ASTGDRHLPGNYGLKDQR 180
             |:|.:|||.|..|:.|  ||....:.....::||.:::.:|..|| |..|.:..|||.||.|||
Frog   137 -VMVFIHGGGFESGTTSLDIYDGSVLAYAENVIVVSMNYRVGAFGFLALPGHKDAPGNAGLFDQR 200

  Fly   181 LALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVI--QQ 243
            ||||||.:|||.|||.||.:.:.|||||.||....|:..........||..||:....|.:  ::
Frog   201 LALQWINENIAAFGGNPDRVTIFGHSAGAASVGFHLISPKSYPYYNRAIVQSGSGTSNWALNSEE 265

  Fly   244 GGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAPD 308
            ..:|.|.:|..::.|..|:..| :..||.::....:..  :..|.......:.|.|:|:..
Frog   266 RAKRLALKLAEVLECPQTDDDA-IITCLLNEDPKHLTE--KQLLAKEPYALTQFLPIVDHD---- 323

  Fly   309 AFLTEDPRAVI-KSGKFAQV----------PWAVTYTTE-----DGGYNAAQLLERNK----LTG 353
             ||.:.|..|: :|.|...:          |:.:..:|:     :...::|:||||.|    ..|
Frog   324 -FLVDVPENVLGQSMKRTDILLGITKDDGNPFTLIGSTDFNIQTESSISSAELLERLKRFFPSAG 387

  Fly   354 ESWIDLLNDRWFDWAPYLLFYRDAKKTIKDMDDLSFDLRQQYLA-----DRRFSVESYWNVQRMF 413
            :..|..:..::.||       .|.....|:...:...||..|.|     ..|::||...|
Frog   388 DLGIQSILLQYKDW-------EDVNNGEKNRQAMELILRDYYFACPVKGFARYAVEHQNN----- 440

  Fly   414 TDVLFKNSVPSAIDLHRKYGKSPVYSFVYDNPTDSGVGQLLSNRTDVHFGTVHGDDFFLIFNTAA 478
                                   |:.:.||:.:.       ::......|.:||.:..::|....
Frog   441 -----------------------VFFYEYDHRSS-------NDPWPEWMGALHGAELPMLFGKPF 475

  Fly   479 YRTGIRPDEEVI-SKKFIGMLEDFALNDKGTLTFGECNF---QNNVNSKEYQVLRIS 531
            ...|.....|:: ||:.:.:..:||......:. .|..|   |.::..::|.||:::
Frog   476 INKGRYTRSELLFSKRIMKLWANFARTGSPNVE-AEDGFVWPQYSLKDEKYAVLKLN 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	146/558 (26%)
Est-P	NP_788501.1	Aes	<107..>240	CDD:223730	54/136 (40%)
bchel	XP_002937472.3	COesterase	31..547	CDD:395084	146/560 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910