Protein Alignment Est-P and nlgn2b

DIOPT Version :9

• Sequence 1: NP_788501.1
• Gene: Est-P / 39393
• FlyBaseID: FBgn0000594
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 611
• Identity: 156/611 - (25%)
• Similarity: 243/611 - (39%)
• Gaps: 189/611 - (30%)

  Fly     5 KRLLCLTLLWI--------------AALESEADPLIVEITNGKIRGKDN-------GLYYSYESI 48
            :|:....|:|:              |.|.:...|: |....||:||...       |....|..:
Zfish    19 RRISDTCLVWLLGLALRLALSSCQRADLTTAKHPM-VTTGYGKLRGVRKELNNEILGPVEQYLGV 82

  Fly    49 PNAEHPTGALRFEAPQ-PYSHHWTDVFNATQSPVECMQ-------------W------------- 86
            |.|..|.|..||:.|: |.|  |.::.||||....|.|             |
Zfish    83 PYATPPVGERRFQPPEAPGS--WQEIRNATQFAPVCPQNIHGVLPEIMLPVWFTDNLDAAAAYVQ 145

  Fly    87 NQFINENNKLMGDEDCLTVSIYKP-------KKPNRSSF--------------PVVVLLHGGAFM 130
            ||          .||||.:::|.|       ||.:.||.              ||::.:|||:||
Zfish   146 NQ----------SEDCLYLNVYVPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVMLFIHGGSFM 200

  Fly   131 FGSGSIYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPGNYGLKDQRLALQWIKKNIAHFGG 195
            .|:|:::....:...|.::||.:::.||.|||.|:||:...|||||.||..||:|:.:||.||||
Zfish   201 EGTGNMFDASVLAAYGNVIVVTMNYRLGVLGFLSSGDQSAKGNYGLLDQIQALRWLNENIGHFGG 265

  Fly   196 MPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQGGRRRAFELGRIVGCGH 260
            .|:.|.:.|..||.:..:|.:|....:.|.:.||:.||:|:..|.:..........|.:.|||.:
Zfish   266 DPERITIFGSGAGASCVNLLILSHHSEGLFQRAIAQSGSAISSWSVNYRPLMYTKILAKKVGCSY 330

  Fly   261 TNVSAELKDCLKSKPASDI----VSAVRSFLVFSYVPFSAFGPVVEPSDAPDAFLTEDPRAVIKS 321
            :: :|:|.|||:.|...::    |...|..:        ||||||:....||     ||..:::.
Zfish   331 SD-TADLVDCLRRKSYRELVDQDVQPARYHI--------AFGPVVDGDVVPD-----DPEILMQQ 381

  Fly   322 GKFAQVPWAVTYTTEDGGYNAAQLLERNKLTGESWIDLLNDRWFDW-----APYLLFYRDAK--- 378
            |:|......:.....:|    .:.::.|:  ||..|...:   ||:     ...|..|.:.|
Zfish   382 GEFLNYDILLGVNQGEG----LKFVDDNE--GEEGISAAS---FDYTISNFVDNLYGYPEGKDIL 437

  Fly   379 -KTIKDM-----DDLSFDLRQQYLADRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRKYGKSPV 437
             :|||.|     |..:.|:|::.|.             .:|||..:.....:...||.:: :|||
Zfish   438 RETIKFMYTDWADRDNGDMRRKTLL-------------ALFTDHQWVAPAVATAKLHAEF-QSPV 488

  Fly   438 YSFVYDNPTDSGVGQLLSNRTDVHFGT---------VHGDDFFLIFNTAAYRTGIRPDEEVISKK 493
            |.:.:.:                |..|         .|||:...:|..                .
Zfish   489 YFYTFHH----------------HCQTEARPEWADAAHGDEIPYVFGV----------------P 521

  Fly   494 FIGMLEDFALNDKGTLTFGECNFQNN 519
            .:|..|.|           .|||..|
Zfish   522 MVGATELF-----------PCNFSKN 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-P	NP_788501.1	Esterase_lipase	26..537	CDD:238191	150/576 (26%)
		Aes	<107..>240	CDD:223730	55/153 (36%)
nlgn2b	NP_001159808.1	COesterase	47..611	CDD:278561	151/583 (26%)
		Aes	<181..>279	CDD:223730	40/97 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575513
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740