Protein Alignment Est-6 and Ache

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_038945765.1
• Gene: Ache / 83817
• RGDID: 69313
• Length: 616
• Species: Rattus norvegicus
• Alignment Length: 564
• Identity: 168/564 - (29%)
• Similarity: 250/564 - (44%)
• Gaps: 135/564 - (23%)

  Fly     8 LIIVLSCLWLGSNASDTDDP-LLVQLPQGKLRG----RDNGSYYSYESIPYAEPPTGDLRFEAPE 67
            |.::||.|..|:.|...:|| |||::..|:|||    ...|...::..||:||||.|..||..||
  Rat    18 LFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPE 82

  Fly    68 PYKQKWSDIFDATKTPVACLQW-DQFTPG--------ANKLVGEEDCLTVSVYKPKNSKRNSFPV 123
            | |:.||.|.|||.....|.|: |...||        .|:.: .||||.::|:.|.....:..||
  Rat    83 P-KRPWSGILDATTFQNVCYQYVDTLYPGFEGTEMWNPNREL-SEDCLYLNVWTPYPRPTSPTPV 145

  Fly   124 VAHIHGGAFMFGAAWQNGHENVMREGKF-------ILVKISYRLGPLGFVS-TGDRDLPGNYGLK 180
            :..|:||.|..||:..:     :.:|:|       :||.::||:|..||:: .|.||.|||.||.
  Rat   146 LIWIYGGGFYSGASSLD-----VYDGRFLAQVEGTVLVSMNYRVGTFGFLALPGSRDAPGNVGLL 205

  Fly   181 DQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPW-VI 244
            ||||||:|:::|||:|||:|.:|.|.|.|||.|||.:.:|......|...|...||....|| .:
  Rat   206 DQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATV 270

  Fly   245 QKG-ARGRAFELGRNVGCE---SAEDSTSLKKCLKSKPASELVT----AVRKFLIFSYVPFAPFS 301
            ..| ||.||..|.|.|||.   :..:.|.|..||:::||.:||.    .:.:..||.:    .|.
  Rat   271 SAGEARRRATLLARLVGCPPGGAGGNDTELISCLRTRPAQDLVDHEWHVLPQESIFRF----SFV 331

  Fly   302 PVLEP---SDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNE 363
            ||::.   ||.|:|:        |.:|.|..:...|..|.::|.
  Rat   332 PVVDGDFLSDTPEAL--------INTGDFQDLQVLVGVVKDEGS--------------------- 367

  Fly   364 RWLELAPYLLFYRDTKTKKDMDDYSRKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDL 428
                   |.|.|......||.:  |...:.:::...|..:...|:|            ..|::.|
  Rat   368 -------YFLVYGVPGFSKDNE--SLISRAQFLAGVRIGVPQASDL------------AAEAVVL 411

  Fly   429 HRK---YGKSPAY------AYVYDNPAEKGIAQVLANRTDYDFGTVHGDDYFLIFEN-------- 476
            |..   :.:.||:      |.|.|:.....:|| ||.|.......|    |..|||:
  Rat   412 HYTDWLHPEDPAHLRDAMSAVVGDHNVVCPVAQ-LAGRLAAQGARV----YAYIFEHRASTLTWP 471

  Fly   477 ------------FVRDVEMRP------DEQIISRNFINMLADFA 502
                        |:..:.:.|      :|:|.::..:....:||
  Rat   472 LWMGVPHGYEIEFIFGLPLDPSLNYTVEERIFAQRLMKYWTNFA 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	159/542 (29%)
		Aes	<110..>243	CDD:223730	57/141 (40%)
Ache	XP_038945765.1	COesterase	37..563	CDD:395084	161/545 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910