Protein Alignment Est-6 and Ces2g

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_932116.2
• Gene: Ces2g / 72361
• MGIID: 1919611
• Length: 560
• Species: Mus musculus
• Alignment Length: 550
• Identity: 153/550 - (27%)
• Similarity: 241/550 - (43%)
• Gaps: 90/550 - (16%)

  Fly     1 MNYVGLGLIIVLSCLWLGSNASDTDDPLLVQLPQGKLRGR------DNGSYYSYESIPYAEPPTG 59
            ::.|..||:::|..: .|.::.:|..  :.....|:::||      .....:::..||:|:||.|
Mouse    10 LDAVFFGLLLLLGHV-QGHDSPETSP--IRSTHSGQVQGRLIHVKDTKAGVHTFLGIPFAKPPVG 71

  Fly    60 DLRF---EAPEPYKQKWSDIFDATKTPVACLQWDQFTPGANKLVG----------EEDCLTVSVY 111
            .|||   |||||    ||.:.|.|..|..|.|  ..|.....|..          .||||.:::|
Mouse    72 PLRFAPPEAPEP----WSGVRDGTSQPAICPQ--NVTMNMEGLKELKLTLPPVSMSEDCLYLNIY 130

  Fly   112 KPKNSKRNS-FPVVAHIHGGAFMFGAAWQNGHENVMREGKFILVKISYRLGPLGFVSTGDRDLPG 175
            .|.:::..| .||:..|||||...|.|.......:......::|.|.||||.|||.||||....|
Mouse   131 TPAHAQEGSNLPVMVWIHGGALTVGMASMYDGSVLAATEDVVVVAIQYRLGVLGFFSTGDEHARG 195

  Fly   176 NYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALD 240
            |:|..||..||:|::||||.|||.|..|.:.|.||||.||...::......|...|...||.||.
Mouse   196 NWGFLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGISVSSHVVSPMSKGLFHRAIMESGVALL 260

  Fly   241 PWVIQKGARGRAFELGRNV--------GCESAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVPF 297
            |        |..|.....|        ||| |.||.:|.:||:.|...|::...:.|.:...|..
Mouse   261 P--------GTIFSFSEVVYQTVAKLSGCE-AMDSEALVRCLRGKSEEEILAISKNFQMIPGVVD 316

  Fly   298 APFSPVLEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKS--GIVIDD 360
            ..|.|             :.|::::.|..|..||..:.:..::.|:....::...::  ||..::
Mouse   317 GEFLP-------------KHPQELLASADFHPVPSIIGFNNDEYGWIVPKVIGSTQTIKGITREN 368

  Fly   361 LNERWLELAPYLLFYRDTKTKKDMDDYSRKIKQEYIGNQRFDIESYSELQRLFT----DILFKNS 421
            |.....:.||.::.         ..:.|..:.:||:.    |||....||..||    |.:|...
Mouse   369 LQAVLKDTAPQMML---------PPECSDLLMEEYME----DIEDPKTLQIQFTEMMEDFMFVIP 420

  Fly   422 TQESLDLHRKYGKSPAYAYVYDNPAEKGIAQVLANRTDYDFGTVHGDDYFLIFENFV--RDVEMR 484
            :.:.....|.:  :|.|.|.:.:.: ..:..|.....:.|    |||:...:|.:|.  ..:.:.
Mouse   421 SLQVAYFQRSH--APVYFYEFQHQS-SFLKDVRPPHVNAD----HGDEVPFVFGSFFWGMKLNLT 478

  Fly   485 PDEQIISRNFINMLADFASSDN---GSLKY 511
            .:|::::|..:...|:||...|   .||.|
Mouse   479 EEEKLLNRRMMKYWANFARHGNPNSESLPY 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	146/521 (28%)
		Aes	<110..>243	CDD:223730	56/133 (42%)
Ces2g	NP_932116.2	COesterase	31..539	CDD:278561	147/527 (28%)
		Aes	72..>337	CDD:223730	98/292 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832652
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840