Protein Alignment Est-6 and Ces2f

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001073334.2
• Gene: Ces2f / 71903
• MGIID: 1919153
• Length: 561
• Species: Mus musculus
• Alignment Length: 527
• Identity: 143/527 - (27%)
• Similarity: 225/527 - (42%)
• Gaps: 104/527 - (19%)

  Fly    35 GKLRGR------DNGSYYSYESIPYAEPPTGDLRF---EAPEPYKQKWSDIFDATKTPVACLQWD 90
            |::||:      .....:::..||:|:||.|.|||   |||||    ||.:.|.|..|..|||.|
Mouse    41 GQVRGKFVHLTDIKAGAHNFLGIPFAKPPVGPLRFAPPEAPEP----WSGVRDGTSQPAMCLQND 101

  Fly    91 QFTPGANKLVG-------------EEDCLTVSVYKPKNSKRNS-FPVVAHIHGGAFMFGAAWQNG 141
            ...    .|.|             .||||.:::|.|.:::..| .||:..:|||..:.|.|....
Mouse   102 DIV----NLEGLKIIKMILPPFSMSEDCLYLNIYTPAHAQEGSNLPVMVWLHGGGLVAGMASMYD 162

  Fly   142 HENVMREGKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLV 206
            ...:......::|...||||..||.||||....||:|..||..||.|::||||:|||.|.:|.|.
Mouse   163 GSVLAATEDVVVVVTQYRLGIPGFYSTGDEQARGNWGFLDQTAALHWVQQNIANFGGNPDSVTLF 227

  Fly   207 GHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQKGARGRAFELGRNVGCESAEDSTSLK 271
            |.||||.||...:|......|...|...||.||.|.:|.........::....|||:: :|.:|.
Mouse   228 GQSAGGTSVSFHVLSPVSQGLFHRAIMESGVALLPTIIPDSPEMIFTKVANLSGCETS-NSEALV 291

  Fly   272 KCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSY 336
            :||:.|..:|::...:.|.....|....|.|             :.|:.::.|..|..||..:..
Mouse   292 RCLRGKSEAEILAMSKAFRFMPAVVDGKFLP-------------RHPKKLLASADFHPVPSIIGV 343

  Fly   337 VTEDGGYNAALLLKERKSGIVIDDLNERWL---------------ELAPYLL--FYRDTKTKKDM 384
            ..::.|:   ::.|..|....|..:|...|               |....|:  :.|||:
Mouse   344 NNDEYGW---IIPKIFKFSQTIRKINRNNLKAIMKITTEQMMLPSECGDLLIEEYLRDTE----- 400

  Fly   385 DDYSRKIK-QEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAEK 448
            |.::.::: :|.||                 |.|......:.....|.:  :|.|.|.:.:.
Mouse   401 DPWTLQMQFREMIG-----------------DFLIIIPALQVARFQRSH--APVYFYEFQHR--- 443

  Fly   449 GIAQVLANRTDYDFGTVHGDDYFLIFENFVRDVE--MRPDEQIISRNFINMLADFASSDNGSLKY 511
              :.:|.....:.....|||:.:|||.:|...::  ...:|:::||..:...|:||       :|
Mouse   444 --SSLLKYFRPWHVKADHGDELYLIFGSFFWGLKFSFTAEEKLLSRKMMKYWANFA-------RY 499

  Fly   512 GECDFKD 518
            |..:.:|
Mouse   500 GNPNSED 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	143/527 (27%)
		Aes	<110..>243	CDD:223730	54/133 (41%)
Ces2f	NP_001073334.2	COesterase	32..540	CDD:395084	143/527 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832656
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840