Protein Alignment Est-6 and ces2a

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001070720.1
• Gene: ces2a / 566132
• ZFINID: ZDB-GENE-061013-99
• Length: 555
• Species: Danio rerio
• Alignment Length: 537
• Identity: 155/537 - (28%)
• Similarity: 224/537 - (41%)
• Gaps: 86/537 - (16%)

  Fly     6 LGLIIVLSCLWLGSNASDTDDPLLVQLPQGKLRG---RDNGS---YYSYESIPYAEPPTGDLRFE 64
            |.|.:.|:.:| .:...:...|:.| |..|.:||   :..||   ...|..||:|:||.|..|..
Zfish     7 LCLCLTLAPVW-SAPVQEDSGPVAV-LKHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGPHRLA 69

  Fly    65 APEPYKQKWSDIFDATKTPVACLQWDQFTPGANKLVG--------EEDCLTVSVYKP-KNSKRNS 120
            ||:|. |.|..|.:||:.|:.|||.....|...|.:.        .||||.::||.| :.::...
Zfish    70 APQPV-QGWEGIRNATEHPLMCLQNPDILPAIAKAIDLEVTAIGVSEDCLYLNVYTPSQRAESEK 133

  Fly   121 FPVVAHIHGGAFMFGAAWQNGHENVMREG-------KFILVKISYRLGPLGFVSTGDRDLPGNYG 178
            .||:..||||....|.|.. ..|..:.:|       |.::|.|.||||.||:.||||:...||:|
Zfish   134 LPVMIWIHGGGLAMGGACM-FKELCLYDGTPLAAYEKVVVVVIQYRLGILGYFSTGDQHAKGNWG 197

  Fly   179 LKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLRE-DFGQLARAAFSFSGNALDPW 242
            ..||..||:|::|||.:|||:||:|.:.|.||||.|..|..|.. ..|...||.|. ||.|....
Zfish   198 FLDQIAALQWVQQNIEAFGGDPQSVTIAGESAGGISASLLTLSPMTKGLFQRAIFQ-SGVATVKG 261

  Fly   243 VIQKGARGRAFELGRNVGCESAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPS 307
            ...|.....|..:.....|:.: .|..|.||::.....:::.|.:|..||             |.
Zfish   262 YFVKDPSTHAQVIANITECDFS-SSEVLVKCIREMTEEQIIKAAQKKGIF-------------PG 312

  Fly   308 DAPDA-IITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERWLELAPY 371
            .|.|. .|...|.:::||..|.:||..:.....:.|:....:.           |.:.|::
Zfish   313 AAVDGEFIKAQPEEILKSKDFQKVPILIGTTNHEFGWMLPQIF-----------LPKEWVK---- 362

  Fly   372 LLFYRDTKTKKD------MDDYSRK---IKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLD 427
               ..|||..||      .|..|..   |..||..|.:...|.......|..||.....:.....
Zfish   363 ---GMDTKAAKDRLGLLNADGASGANGIIADEYFKNAKTPEEIRDAFTELLGDIFMVIPSITVAS 424

  Fly   428 LHRKYGKSPAYAYVYDN-PAEKGIAQVLANRTDYDFGTV-HGDDYFLIFENFVRDVEMR------ 484
            .||:.| .|.|.|.:.: |:       .||:....|... |.||...:|.....||.::
Zfish   425 YHREAG-VPVYMYEFQHGPS-------TANKFRPSFVKADHADDVGFVFGACFWDVHVKGLGTLT 481

  Fly   485 PDEQIISRNFINMLADF 501
            .:|..:.|..:...|:|
Zfish   482 EEENQLCRTVMKYRANF 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	150/514 (29%)
		Aes	<110..>243	CDD:223730	58/141 (41%)
ces2a	NP_001070720.1	COesterase	21..541	CDD:278561	151/522 (29%)
		Aes	<122..346	CDD:223730	79/239 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575323
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.930