Protein Alignment Est-6 and ces2b

DIOPT Version :10

• Sequence 1: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_021326380.1
• Gene: ces2b / 561967
• ZFINID: ZDB-GENE-041014-96
• Length: 1611
• Species: Danio rerio
• Alignment Length: 545
• Identity: 157/545 - (28%)
• Similarity: 240/545 - (44%)
• Gaps: 101/545 - (18%)

  Fly     9 IIVLSCLWLGSNASDTDDPLLVQLPQG-------KLRGRDNGSYYSYESIPYAEPPTGDLRFEAP 66
            :.:|..:.|.::....|.|:| |...|       |.||:|. ..:||..||:|:||.|.||...|
Zfish    11 LCILIAVTLQNSVKAEDGPIL-QTNSGALKGLQMKARGKDT-VIHSYLGIPFAKPPVGPLRLAPP 73

  Fly    67 EPYKQKWSDIFDATKTPVACLQWDQ--------FTPGANKLVGEEDCLTVSVYKPKNSKRN-SFP 122
            :| .:||..:.||||.|:.|||..|        .:...:.:...||||.::||.|....|| ..|
Zfish    74 QP-AEKWEGVRDATKQPLMCLQDRQLVEDLVANLSAKVDMVDSSEDCLYLNVYTPSKPGRNDKLP 137

  Fly   123 VVAHIHGGAF-MFGAAWQNGH-----ENVMREGKFILVKISYRLGPLGFVSTGDRDLPGNYGLKD 181
            |:..||||.| ...|:..:||     ::|      ::|.|.||||.|||.||||.:.||||||.|
Zfish   138 VMVWIHGGGFTTCSASLFDGHVLAAYQDV------VVVVIQYRLGLLGFFSTGDENAPGNYGLLD 196

  Fly   182 QRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQK 246
            |..||:|:::||.||||:|.:|.:.|.||||.||.|.:|......|...|.:.||.|....::..
Zfish   197 QVAALQWVQENIHSFGGDPGSVTIFGESAGGISVSLHVLSPLSANLFHRAIAESGTAAMEAIMNV 261

  Fly   247 GARGRAFELGRNVGCESAEDSTSLKK---CLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPSD 308
            .....|..:|...||    |.:|.||   ||..|...|::....:..:|.      |...::...
Zfish   262 NPLPIAQAIGNASGC----DISSTKKIVDCLMQKSEVEILKITMENPLFR------FGVTIDGQF 316

  Fly   309 APDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDD--LNERWL----- 366
            .|     :...::.:|.:|.:|| .::.||:|            :.|.|:.:  |...|:
Zfish   317 LP-----RPAAELFQSQQFNKVP-LMTGVTDD------------EIGFVLPNYLLPPDWINGLDL 363

  Fly   367 -ELAPYLLFYRDTKTKKDMDDYS--RKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDL 428
             .:.|.|..:...     :.|.|  ..:..||:|.....|......:.:..|.:|....:::...
Zfish   364 ESILPLLTVFNPA-----LQDQSVLELLLNEYLGTSPDRIRIRDGFREMLGDFMFNIPARQTASY 423

  Fly   429 HRKYGKSPAYAYVYDNPAEKGIAQVLANRTDYDFGTVHGDDYFLIF------------ENFVRDV 481
            ||..| :|.|.|.:.:|     ..||..:.....|:.|||:...:|            ||
Zfish   424 HRDAG-APVYVYEFRHP-----PSVLQRKRPSFSGSDHGDEIVFVFGYCFSEGPIGMAEN----- 477

  Fly   482 EMRPDEQIISRNFINMLADFASSDN 506
             :..:|..:.|..:....:||.:.|
Zfish   478 -LSDEEDELCRTTMAYWGNFAHTGN 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	153/525 (29%)
ces2b	XP_021326380.1	COesterase	27..539	CDD:395084	155/529 (29%)
		COesterase	553..1065	CDD:395084
		COesterase	1079..1592	CDD:395084