Protein Alignment Est-6 and LOC4576397

DIOPT Version :10

• Sequence 1: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_001237723.3
• Gene: LOC4576397 / 4576397
• VectorBaseID: AGAMI1_007721
• Length: 597
• Species: Anopheles gambiae
• Alignment Length: 572
• Identity: 176/572 - (30%)
• Similarity: 263/572 - (45%)
• Gaps: 75/572 - (13%)

  Fly    11 VLSCLWLGS-----------------NASDTDDPLLVQLPQGKLRG--RDNGSYYSYES---IPY 53
            |:||...||                 :..||.|...|.:..|.|.|  ||......:|:   ||:
Mosquito    21 VVSCTSSGSPLLVRAALEPNTACASADEVDTGDAPRVCIDDGCLVGTLRDGMGGEQFEAFLGIPF 85

  Fly    54 AEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQWDQFTPGANKLVGEEDCLTVSVYKPKN-SK 117
            |:||.|:|||..|.|....:..:::|:.....|||.:...|.. .:.|.||||.::||:||. ..
Mosquito    86 AQPPVGELRFADPLPNGPWFEQLYNASYERDMCLQRNDLLPNP-PVTGSEDCLYLNVYRPKECDD 149

  Fly   118 RNSFPVVAHIHGGAFMFGAAWQ--NGHENVMREGKFILVKISYRLGPLGFVSTGDRDLPGNYGLK 180
            |.:.||:.:||||.|..|.|..  .|.|.::...:.|||.:.||||.|||:||||...|||:|||
Mosquito   150 RTNLPVIVYIHGGGFFSGTASSLIVGPEYILDTKRAILVTVQYRLGVLGFLSTGDTAAPGNFGLK 214

  Fly   181 DQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQ 245
            ||.|||:|:|:||..|||..|.:.:||.|||.||||:.|:......|...|...|||:|.||.|.
Mosquito   215 DQTLALRWVKRNIRRFGGNEQLITIVGQSAGAASVHMHMISPLSRGLFERAIMMSGNSLVPWNIP 279

  Fly   246 KG---ARGRAFELGRNVGCESAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPS 307
            ..   |..|:..:..:|..........|...|:..|..:||..|.|..::|..|...|.||:||.
Mosquito   280 TKDPLALARSTAMVVDVMGADRLSGKQLVAALRDIPGEKLVGNVHKLKLWSVDPLTLFRPVVEPK 344

  Fly   308 DAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERWLELAPYL 372
            |:|:..:|::|:...::|.:.|||:...:|..:|...|..:.|:   ..:..:|...:..:.|.|
Mosquito   345 DSPNPFLTEEPKVSWRNGNYQQVPYLAGFVPNEGAIRALSIFKD---ATLFGELQRNFSTILPIL 406

  Fly   373 LFYRDTK--TKK-------DMDDYSRKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDL 428
            |....:|  |:|       |..| ...::|:.:  |.| ::.|||...::...|.......:.|.
Mosquito   407 LEQPPSKALTEKMRTRCLNDTTD-DEPVRQDNL--QGF-VDLYSEAAFIYPVQLGVRQYITAADT 467

  Fly   429 HRKYGKSPAYAYVYDNPAEKGIAQVLANRTDYDFGTVHGDDYFLIFENFVRDVEMRPD------E 487
            .|    :||..|..........:.:.|.....|:|.||.||...:|    |...:.||      |
Mosquito   468 DR----APASVYKLSYKGRYSYSAIYAGGDTSDYGVVHCDDLNYLF----RQPAIFPDYPAGAPE 524

  Fly   488 QIISRNFINMLADFA--------------SSDNGSLKYGECDFKD--NVGSE 523
            ..:...|:|...|||              .::|...:..:||.::  .||.:
Mosquito   525 LKMVDTFVNFFIDFAINGRATPLAPVRECRNENQVYQSLDCDVQEFVRVGDD 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	168/537 (31%)
LOC4576397	XP_001237723.3	None