Protein Alignment Est-6 and Nlg3

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Alignment Length: 634
• Identity: 155/634 - (24%)
• Similarity: 231/634 - (36%)
• Gaps: 194/634 - (30%)

  Fly    19 SNASDTDDPLLVQLPQG--------------KLRGRDNGSYYSYESIPYAEPPTGDLRFEAPEPY 69
            ||.|...|.|..||...              :|.||......:|..||||.||.|:||| .|...
  Fly   140 SNYSPNHDQLPAQLSSRIINTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRF-MPPVS 203

  Fly    70 KQKWSDIFDATKTPVACLQ-----------WDQFTPGANKLV---------GEEDCLTVSVYKP- 113
            ...||.:..|.:....|.|           .::...|..:.:         ..||||.:::|.|
  Fly   204 AAMWSGVKKADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPI 268

  Fly   114 ----KNSKRNS------------------------------------FPVVAHIHGGAFMFGAAW 138
                ::|..:|                                    :||:..:||.::    .|
  Fly   269 QVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESY----EW 329

  Fly   139 QNGHE---NVMRE-GKFILVKISYRLGPLGFVSTG-DR--DLPGNYGLKDQRLALKWIKQNIASF 196
            .:|:.   :|:.. |:.::|.|:||||.|||::.. ||  .||.||||.|...||.|:|:|||:|
  Fly   330 NSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAF 394

  Fly   197 GGEPQNVLLVGHSAGGASVH--LQMLREDFGQLARAAFSFSGNALDPWVIQKGARGRAFELGRNV 259
            ||:|.::.|.||..|.|.||  :..:....|.|...|...||:.|.||.:.......|..:..:|
  Fly   395 GGDPNSITLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHV 459

  Fly   260 GCESAEDSTSLKKCLKSKPASELVTAVRKFLIF----------------SYVPFAPFSPVLE-PS 307
            .|.|......|.|||:.|...:|::...:...|                .|||.||.||..: .:
  Fly   460 NCASDLPHAHLMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQA 524

  Fly   308 DAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGY-------NAALLLKERKSGIVIDDLNERW 365
            .|..|         ..:|..|:...|.:     ||:       |..|:.|...:.:...||....
  Fly   525 QASTA---------AGNGLGGEAGIAAA-----GGWGTPGQLENIVLMRKTAINKLSRYDLMAGV 575

  Fly   366 LELAPYLLFYR-DTKTKKDMDDYSRKIKQEYIGNQRFDI-ESYSELQRLFTD--------ILFKN 420
            .....:..|.. |.:...:.|..||.:|........|.: |.::.:...:||        |..::
  Fly   576 TRAEAFFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRD 640

  Fly   421 STQESL-------------DLHRKYGKSPAYAYVYDNPAEKGIAQVLANRTDYD--FGTVHGDDY 470
            .|.|:|             |||....:: :|.||:|.....|         ||.  .|.:||:|.
  Fly   641 ETLEALSDAQVVAPAAQTVDLHSADHRN-SYLYVFDYQTRFG---------DYPQRQGCIHGEDL 695

  Fly   471 FLIF------------------------------ENFVRDVEMRPDEQI 489
            ..||                              .||||  ...|:||:
  Fly   696 PYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVR--TGNPNEQM 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	150/624 (24%)
		Aes	<110..>243	CDD:223730	55/182 (30%)
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	150/623 (24%)
		Aes	<313..>410	CDD:223730	40/100 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440317
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740