Protein Alignment Est-6 and alpha-Est5

DIOPT Version :10

• Sequence 1: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 145/540 - (26%)
• Similarity: 239/540 - (44%)
• Gaps: 74/540 - (13%)

  Fly    32 LPQGKLRGRDNGS-----YYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQWDQ 91
            ||.|:::|....|     |:|:|.||:|:||.|:|||.||.| ...||.:.|.|.......|...
  Fly    15 LPVGQIKGVKRLSLYDDPYFSFEKIPFAKPPLGELRFRAPVP-ADPWSGVLDCTHYAEKPTQRGL 78

  Fly    92 FTPGANKLVGEEDCLTVSVYKPKNSKRNSFPVVAHIHGGAFMFGAAWQN--GHENVMREGKFILV 154
            .|   .::.|.||||.::||..:.......||:.:|:||||..|.|.:.  |.:..|.: ..:||
  Fly    79 LT---REIEGGEDCLYLNVYSKQLKSEKPLPVMVYIYGGAFTVGEATRELYGPDYFMTK-DVVLV 139

  Fly   155 KISYRLGPLGFVSTGDRDL--PGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHL 217
            .::||:..|||:|..|..|  |||.|||||.|||||:||.|::|.|:..|:.:.|.||||.|.|.
  Fly   140 TLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGGCSTHF 204

  Fly   218 QMLREDFGQLARAAFSFSGNALDPWVIQKGARGRAFELGRNVGCESAEDSTSLKKCLKSKPASEL 282
            .|..|....|...|...||...:.|. ...|...||.|.:..|.....|...:.:.|:..||.:|
  Fly   205 MMCTEQTRGLFHKAIPMSGTVHNYWA-NNPAEDFAFRLAQQNGFTGENDDAKVLEYLQGVPARDL 268

  Fly   283 VT-------AVRKFLIFSYVPFAPFSPVLEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTED 340
            |.       ..|..|:|:      |.|.:|.....|.::.:.|.::.:..      |:.::....
  Fly   269 VNHNLLTPEHRRNGLLFA------FGPTVEAYVGEDCVVPKPPVEMARDA------WSNNFPVML 321

  Fly   341 GG--YNAALLLKERKSGI-VIDDLNERWLELAPYLLFYRDTKTKKDMDDYSRKIKQEYIGNQRFD 402
            ||  :....:.....:.: .:|.|::....|.|  :..|...::|:..:||:::.:.|.|.....
  Fly   322 GGTSFEGLFMYPAVSANLKALDSLSQDPTRLVP--VDVRTVSSEKENLEYSQRLMKAYFGYSPPS 384

  Fly   403 IESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAEKGIAQVLANRTDYDF----- 462
            .|....:...::..:|.:....:.:....|.|:|.|.|.:|           .:..:::|
  Fly   385 SELLLNMLDFYSYKIFWHGFNRTFNARLTYAKAPTYYYRFD-----------FDSPNFNFYRAKF 438

  Fly   463 -------GTVHGDDYFLIFENF------VRDVEMRPDEQIISRNFINMLADFASSDNGSL-KYGE 513
                   |..|.||...:|.|.      ....|.|..|::     |.:...||::.|.:. :.|.
  Fly   439 CGDKIKTGVAHADDLSYLFRNAGSWKLDKTSAEYRTIERM-----IGIWTAFAATSNPNCPEIGH 498

  Fly   514 CDFKDNVGSEKFQLLAIYID 533
            .::|.:..::..:::.|..|
  Fly   499 LEWKPSTKNDPKRVINISSD 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	145/540 (27%)
alpha-Est5	NP_001246965.1	alpha/beta hydrolases	12..533	CDD:473884	145/540 (27%)