Protein Alignment Est-6 and Nlg2

DIOPT Version :10

• Sequence 1: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Alignment Length: 594
• Identity: 146/594 - (24%)
• Similarity: 238/594 - (40%)
• Gaps: 158/594 - (26%)

  Fly     8 LIIVLSCLWL--------GSNASDTDDPLLVQLPQGKLRG---RDNGSYYSYESIPYAEPPTGDL 61
            ::::|:.||.        |||.        |:...|.|||   |.:....::..||||.||.|.|
  Fly   163 VLLLLTSLWPDCCECLHGGSNT--------VKTKYGLLRGIVVRSSPLVEAFLGIPYASPPVGSL 219

  Fly    62 RFEAP-EPYKQKWSDIFDATKTPVACLQWDQFTPGANKLVGE--------------------EDC 105
            ||..| .|  ..|..:..|.:....|.|.....|...:.:.|                    |||
  Fly   220 RFMPPITP--STWKTVRSADRFSPVCPQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDC 282

  Fly   106 LTVSVYKP---KNSKRNS----------FPVVAHIHGGAFMFGAAWQNGH----ENVMREGKFIL 153
            |.:::|.|   :..:||:          ...|..|||.::    .|.:|:    ..:...|..|:
  Fly   283 LYLNIYVPYETRRQRRNTDDTTGEPKTKLSTVVFIHGESY----DWNSGNPYDGSELAAHGNVIV 343

  Fly   154 VKISYRLGPLGFVSTGDRD-LPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHL 217
            |.|::|||..||:.||.:: ..||:||.|....|.|:|:|:.:|||:||::.|:|:..|....::
  Fly   344 VTINFRLGIFGFLKTGGKESAQGNFGLMDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANI 408

  Fly   218 QMLREDFGQLARAAFSFSGNALDPWVIQKGARGRAFELGRNVGCESAEDSTSLKKCLKSKPASEL 282
            .::......|.:.....||:||.||.|||........:....||........|..||::|..:||
  Fly   409 LVVSPVASDLIQRTVLVSGSALSPWAIQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRTKSVAEL 473

  Fly   283 VTAVR----KFLIFSYVPFAPF--SPVLEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDG 341
            : ||:    :||    |.||||  ..|:.|...|....|              :|...:.|:..|
  Fly   474 L-AVKVDHPRFL----VGFAPFVDGTVISPGANPLGSTT--------------LPLGSAIVSTSG 519

  Fly   342 GYNAALLLKERKSGIVIDDLN-------------ERWLELAPYLLFYRDTKTKKDMDDYSRKIKQ 393
                            |:..|             |.:|:|:...|.:...:|::|      :|.:
  Fly   520 ----------------IEYANFPKRDLIFCLTSVESYLDLSAQDLEFGFNETRRD------RILR 562

  Fly   394 EYIGNQ-RFDI-ESYSELQRLFTD--------ILFKNSTQESL-DLHRKYGKSPAYAYVYDNPAE 447
            .::.|. .:.: |.::.|:..:||        :..:::|.:.| |.|.   .||.....|.:...
  Fly   563 TFVRNNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDATLQFLSDGHT---ASPLIKLGYMHSLR 624

  Fly   448 KGIAQVL--ANRT---DYD--FGTVHGDDYFLIFENFVRDVEMRP--------DEQIISRNFINM 497
            .|.|..|  .::|   :|.  .|:|.|:|.     .|...:.|.|        .|:.|.|..:..
  Fly   625 GGRAYFLHFKHKTIEEEYPQRSGSVRGEDV-----PFWLGLPMSPLFPHNYTTQERQIGRLMLRY 684

  Fly   498 LADFASSDN 506
            |::||.:.|
  Fly   685 LSNFAKTGN 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	140/565 (25%)
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	142/575 (25%)