Protein Alignment Est-6 and Ces2g

DIOPT Version :10

• Sequence 1: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001099645.1
• Gene: Ces2g / 291952
• RGDID: 1308358
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 154/551 - (27%)
• Similarity: 237/551 - (43%)
• Gaps: 92/551 - (16%)

  Fly     1 MNYVGLGLIIVLSCLWLGSNASDTDDPLL---VQLPQGKL-RGRD-NGSYYSYESIPYAEPPTGD 60
            :|.|..||:::|  :.:....|....|:.   ....|||| ..:| ....:::..||:|:.|.|.
  Rat    10 LNAVLFGLLLLL--IHVQGQHSPESSPIRNTHTGQVQGKLTHSKDFKSGVHTFLGIPFAKAPVGP 72

  Fly    61 LRF---EAPEPYKQKWSDIFDATKTPVACLQWDQFTPGANK--------LVGEEDCLTVSVYKPK 114
            |||   |||||    ||.:.|.|.....|.|..:......|        :...||||.:::|.|.
  Rat    73 LRFAPPEAPEP----WSGVRDGTSQSNICPQNVRMNMEGLKEMKLTLPPVSMSEDCLYLNIYAPA 133

  Fly   115 NSKRNS-FPVVAHIHGGAFMFGAAWQNGHENVMREGKFILVKISYRLGPLGFVSTGDRDLPGNYG 178
            ::...| .||:..|||||...|.|.......:......::|.|.||||.|||.||||....||:|
  Rat   134 HAHEGSHLPVMVWIHGGALTVGMASMYDGSMLAATEDVVVVTIQYRLGVLGFFSTGDHHARGNWG 198

  Fly   179 LKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWV 243
            ..||..||:|::||||.|||.|..|.:.|.||||.||...::......|...|...||.||.|
  Rat   199 YLDQVAALRWVQQNIAHFGGNPDCVTIFGESAGGLSVSSHVVSPMSKGLFHRAIMESGVALMP-- 261

  Fly   244 IQKGARGRAFELGRNV--------GCESAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVPFAPF 300
                  |..|.....|        ||| |.|..||..||:.|...::....::|.:...|....|
  Rat   262 ------GTIFNFSEMVYQMVVKLSGCE-AMDPESLVHCLRGKSEEQITVISKEFQMIPAVVDGEF 319

  Fly   301 SPVLEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKS--GIVIDDLNE 363
            .|             ..|::::.|..|..||..:.:..::.|:....::...::  ||..::|..
  Rat   320 LP-------------NHPQELLASADFHPVPSIIGFNNDEYGWIVPKVIGSAQTIKGITRENLQA 371

  Fly   364 RWLELAPYLLFYRDTKTKKDMDDYSRKIKQEYIGNQRFDIESYSELQRLFT----DILFKNSTQE 424
            ...:.||.::.         ..:.|..:.:||:|    |||....||..||    |.:|...:.:
  Rat   372 FLKDTAPQMML---------PPECSDLLMEEYMG----DIEDPQTLQAQFTEMMEDFMFVIPSLQ 423

  Fly   425 SLDLHRKYGKSPAYAYVYDNPAE--KGI--AQVLANRTDYDFGTVHGDDYFLIFENFV--RDVEM 483
            .....|.:  :|.|.|.:.:.:.  |.|  ..|.|:         |||:...:|.:|.  ..:.:
  Rat   424 VARFQRSH--APVYFYEFQHQSSFLKDIRPPHVKAD---------HGDEVPFVFGSFFWGMKLNL 477

  Fly   484 RPDEQIISRNFINMLADFA---SSDNGSLKY 511
            ...|::::|..:...|:||   :.::.||.|
  Rat   478 TEGEKLLNRRMMKYWANFARYGNPNSNSLPY 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	147/523 (28%)
Ces2g	NP_001099645.1	COesterase	32..539	CDD:395084	148/527 (28%)