Protein Alignment Est-6 and Ces2a

DIOPT Version :10

• Sequence 1: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_653344.1
• Gene: Ces2a / 246252
• RGDID: 708353
• Length: 558
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 158/543 - (29%)
• Similarity: 250/543 - (46%)
• Gaps: 97/543 - (17%)

  Fly     4 VGLGLIIVLSCLWLGSNASDTDDPLLVQLPQGKLRG-----RDNGS-YYSYESIPYAEPPTGDLR 62
            |..||:::|..:    :..|:..|:. ....|::||     :|..| .:::..||:|:||.|.||
  Rat    13 VACGLLLLLQHV----HGQDSASPIR-NTHTGQVRGSFVHVKDTKSGIHTFLGIPFAKPPVGPLR 72

  Fly    63 F---EAPEPYKQKWSDIFDATKTPVACLQWDQF--------------TPGANKLVGEEDCLTVSV 110
            |   |.|||    ||.:.|||..|..|||.|..              ||.:      ||||.:::
  Rat    73 FAPPEDPEP----WSGVRDATSQPAMCLQTDIMNLDGIKEMKLTVHPTPMS------EDCLYLNI 127

  Fly   111 YKPKNSKRNS-FPVVAHIHGGAFMFGAAWQNGHENVMREGKFILVKISYRLGPLGFVSTGDRDLP 174
            |.|.:::..| .||:..||||..:.|:|..|....:....:.::|.|.||||.|||.||||::..
  Rat   128 YTPAHAREGSNLPVMVWIHGGGLVLGSASMNDASTLAATEEIVIVSIQYRLGVLGFFSTGDQNAR 192

  Fly   175 GNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNAL 239
            ||:|..||..||:|::||||.|||....|.:.|.||||.||...::......|...|...||.||
  Rat   193 GNWGYLDQVAALRWVQQNIAYFGGNHGKVTIFGGSAGGTSVSSHVVSPMSKGLFHGAIMQSGVAL 257

  Fly   240 DPWVIQKGARGRAFELGRNVGCESAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPVL 304
            .|.:|...:......:....||| |.||.:|.:||::|...|::...:.|.:...|....|.|
  Rat   258 LPDLISDKSEVVYKTVANLSGCE-APDSEALIRCLRAKSKQEILAINQVFKMIPGVVDGKFLP-- 319

  Fly   305 EPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGI--VIDDLNERWLE 367
                       :.|::::.||.|..||..:...|::.|:...:.|     |:  :|..:..   |
  Rat   320 -----------KHPQELLASGDFHPVPSIIGINTDECGWGIPVFL-----GLDHIIKKITR---E 365

  Fly   368 LAPYLLFYRDTKTKK-------DMDDYSRKIKQEYIGNQRFDIESYSELQRLFT----DILFKNS 421
            ..|.:|  :.|..:.       |:      |.:||:|    |.|:...||..|.    |.:|
  Rat   366 TLPTVL--KSTAAQMMLPPECIDL------IMEEYMG----DTENPETLQEQFRHMLGDFMF--- 415

  Fly   422 TQESLDL-HRKYGKSPAYAYVYDNPAEKGIAQVLANRTDYDFGTVHGDDYFLIFENFV--RDVEM 483
            ...:|.: |.:..::|.|.|.:.: ....|.||..:....|    ||||...:|.:::  ...::
  Rat   416 VIPALQVAHFQRSQAPVYFYEFQH-LPSFIKQVRPSHVKAD----HGDDILFVFGSYLWGMTFDL 475

  Fly   484 RPDEQIISRNFINMLADFASSDN 506
            ..:|:::.|..:...|:||.:.|
  Rat   476 TEEEELLKRRVMKYWANFARTGN 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	152/518 (29%)
Ces2a	NP_653344.1	COesterase	30..537	CDD:395084	153/522 (29%)