Protein Alignment Est-6 and Tg

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_006520808.2
• Gene: Tg / 21819
• MGIID: 98733
• Length: 2767
• Species: Mus musculus
• Alignment Length: 552
• Identity: 153/552 - (27%)
• Similarity: 237/552 - (42%)
• Gaps: 97/552 - (17%)

  Fly    35 GKLRGRDNGS-----------YYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQ 88
            |:|:|   ||           .|.:..:|||.||..|.||.|||..  .|:..:||||...:|.|
Mouse  2206 GQLQG---GSQVIKVGTAWKQVYRFLGVPYAAPPLADNRFRAPEVL--NWTGSWDATKPRASCWQ 2265

  Fly    89 WDQFTPGANKLVGEEDCLTVSVYKPKNSKRNSFPVVAHIHGGAFMFGAAWQNGHEN--VMREGKF 151
            ....||...::  .||||.::|:.|:|...|: .|:...|....|.|:..|...:.  :...|.|
Mouse  2266 PGTRTPTPPQI--NEDCLYLNVFVPENLVSNA-SVLVFFHNTMEMEGSGGQLTIDGSILAAVGNF 2327

  Fly   152 ILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGG--AS 214
            |:|..:||||..||:|:|..::.||:||.||..||.|::.:|.:|||:||.|.|....:|.  ||
Mouse  2328 IVVTANYRLGVFGFLSSGSDEVAGNWGLLDQVAALTWVQSHIGAFGGDPQRVTLAADRSGADVAS 2392

  Fly   215 VHLQMLREDFGQLARAAFSFSGNALDPWVI--QKGARGRAFELGRNVGC--ESAEDSTSLKKCLK 275
            :||.:.|....||.|.|....|:||.|..|  .:.|:.:|..|.:.|||  .|.::..|   ||:
Mouse  2393 IHLLISRPTRLQLFRKALLMGGSALSPAAIISPERAQQQAAALAKEVGCPTSSIQEVVS---CLR 2454

  Fly   276 SKPASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTED 340
            .|||:.|..|..|.|..| .||..:.||::     ...:.:.|...:|.....:|...:....:|
Mouse  2455 QKPANILNDAQTKLLAVS-GPFHYWGPVVD-----GQYLRELPSRRLKRPLPVKVDLLIGGSQDD 2513

  Fly   341 GGYNAALLLK--ERKSGIVIDDLNERWLELAPYLLFYRDTKTKKDMDDYSRKIKQEYIG--NQRF 401
            |..|.|..:|  |...|    ..|.:       ..||:..:.....:|...:|....:.  :...
Mouse  2514 GLINRAKAVKQFEESQG----RTNSK-------TAFYQALQNSLGGEDSDARILAAAVWYYSLEH 2567

  Fly   402 DIESYSELQRLFTDILFKNSTQE-----------SLDLHRKYGKSPAYAYVYDNPAE--KGIAQV 453
            ..:.|:...|     ..:|:|::           ||...|..|.    .::|..|..  .|..::
Mouse  2568 STDDYASFSR-----ALENATRDYFIICPMVNMASLWARRTRGN----VFMYHVPESYGHGSLEL 2623

  Fly   454 LANRTDYDFGTVHGDDYFLIFENFVRDVEMRPDEQIISRNFINMLADFASSDNG------SLKYG 512
            ||: ..|.||.    .::..::.     :...:||.:|...:...::|..|.|.      |.|..
Mouse  2624 LAD-VQYAFGL----PFYSAYQG-----QFSTEEQSLSLKVMQYFSNFIRSGNPNYPHEFSRKAA 2678

  Fly   513 EC-----DFKDNVGSEKFQLLAIYIDGCQNRQ 539
            |.     ||....|.|.::.|:..:   .|||
Mouse  2679 EFATPWPDFIPGAGGESYKELSAQL---PNRQ 2707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	150/548 (27%)
		Aes	<110..>243	CDD:223730	52/136 (38%)
Tg	XP_006520808.2	TY	34..93	CDD:238114
		TY	96..161	CDD:238114
		TY	301..359	CDD:238114
		TY	<612..658	CDD:238114
		TY	661..726	CDD:238114
		TY	730..>776	CDD:381826
		TY	<893..922	CDD:381826
		TY	1005..1074	CDD:238114
		TY	1150..1211	CDD:238114
		Ephrin_rec_like	1464..1509	CDD:311571
		TY	1519..1566	CDD:214561
		COesterase	2198..2717	CDD:365897	153/552 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832788
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930