Protein Alignment Est-6 and cest-28

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_504691.2
• Gene: cest-28 / 187305
• WormBaseID: WBGene00019654
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 142/547 - (25%)
• Similarity: 228/547 - (41%)
• Gaps: 98/547 - (17%)

  Fly    39 GRDNGSYY--------SYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQWDQFTPG 95
            |...|:.|        .|..||:|:|.   :||:.||| ...|.::.|.||....|.|...|...
 Worm    22 GPIQGNVYRIGDKTVDGYLGIPFAKPL---VRFKKPEP-AGTWEEVRDCTKYGPRCPQSGPFAEA 82

  Fly    96 AN----KLVGEEDCLTVSVYKPKNSKRN---SFPVVAHIHGGAFMFGAAWQNGHENV-----MRE 148
            .|    .:..|.:|||::|:...:..:|   :.||:.:||||.:...|:......:|     :::
 Worm    83 INFQKDDIPDEANCLTLNVFSKISDSKNFNKTRPVMVYIHGGGYECSASRDYCDYSVAGTLPLKD 147

  Fly   149 GKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGA 213
              .::|.::||:|.|||.:|||...|||:.|.|..|.|.||:::|.||||:|.|:.:.|.|||.|
 Worm   148 --VVVVTLNYRVGILGFFTTGDTVCPGNFALWDLTLGLNWIQKHIESFGGDPGNITIFGQSAGAA 210

  Fly   214 SVHLQMLREDFGQLARAAFSFSGNALDPWVIQKGARGRA---FELGRNVGCESAEDSTSLKKCLK 275
            .|.|..|......|.......||.||..:.: :.|..:|   :|..|::|.:.. :|.:|...:|
 Worm   211 CVDLLALSPHSRDLFNRVIVMSGGALCEYAV-RTANSQAKVCYEFARHLGYDGT-NSQTLFNWMK 273

  Fly   276 SKPASELVTAVRKFLIFSYVP---FAPFSPVLEPSDAP---DAIITQDPRDVIKSGKFGQVPWAV 334
            |||..|    :.|...|. ||   ...::|.|:....|   |.:....|:..|..|
 Worm   274 SKPLEE----IEKMNGFQ-VPASGILAWTPNLDDDFFPKSLDELRIGAPKKDIMMG--------- 324

  Fly   335 SYVTEDGGYNAALLLKERKSGIVIDDLNERWLELAPYLLFYRDTKTKKDMDDY----SRKIKQEY 395
              ..|..|.....|:|:....:             ..|..|.:...|||..|:    ..||.:.|
 Worm   325 --FAEHEGLFFEFLIKDPTPPL-------------EALKLYVNEYYKKDTGDHFEATRNKIIEFY 374

  Fly   396 IGNQRFDIESYSELQRLFT---DILFKNSTQESLDLHRKYGKSPAYAYVYD--NPAEKGIAQVLA 455
            ..|.. |.:..|..:||..   |.||.....::.....|:|.: .:.|::|  ||:..|
 Worm   375 SRNVE-DTDEKSTKERLIDFVGDALFTAGVFDNAKNCLKHGNN-VWLYIFDYCNPSGFG------ 431

  Fly   456 NRTDY--DFGTVHGDDY-FLIFENFVRDVEMRPDEQIISRNFINMLADFASSDNGSLKYGECDFK 517
            |:.::  .....|..|. :::.|....|.:...:|..:......:.::||       |||..:..
 Worm   432 NQEEFMTFVAPTHCTDLRYVLGEGLYSDFQPTEEEHKMIEKMTTIYSNFA-------KYGNPNEH 489

  Fly   518 DNVGSEKFQLLAIYIDGCQNRQHVEFP 544
            .:...|||.|     |..:....:.:|
 Worm   490 GSSEWEKFTL-----DNPRRHFQISYP 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	141/538 (26%)
		Aes	<110..>243	CDD:223730	49/140 (35%)
cest-28	NP_504691.2	COesterase	17..516	CDD:278561	142/547 (26%)
		Aes	<112..>222	CDD:223730	42/111 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810