Protein Alignment Est-6 and cest-9.1

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001359584.1
• Gene: cest-9.1 / 181383
• WormBaseID: WBGene00007692
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 556
• Identity: 123/556 - (22%)
• Similarity: 202/556 - (36%)
• Gaps: 149/556 - (26%)

  Fly    29 LVQLPQGKLRG-----RDNGSYYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQ 88
            ::|...|||||     .|....|.::|:|:|:||.|:|||..|: ..:.||.|.||:|...||:.
 Worm    20 VIQTSYGKLRGITVWSNDKNHRYMFKSVPFAKPPVGNLRFAKPQ-NPESWSGILDASKYSPACMS 83

  Fly    89 WDQFTPGANKLVGEEDCLTVSVYKPKNSKRNSFPVVAHIHGGAFMFGAAWQNGHENVMREGKFIL 153
            ....|....|.. .||||.::::..:....:..||:.:.||||:...:|       :|....|||
 Worm    84 NSSSTSTPQKHY-SEDCLYINIFTSEKCLNSKCPVIVYFHGGAYNLDSA-------IMFNDTFIL 140

  Fly   154 ----------VKISYRLGPLGFVSTGDRD-LPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVG 207
                      |..:.|||..|.:..|..| |..|..|.|...||.::...|..|||:.:.|..:|
 Worm   141 DRYAAEDVVFVIPAVRLGVFGQLYFGPSDLLSENLFLYDAVQALSFVHSEINYFGGDSKRVTAMG 205

  Fly   208 HSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWV------IQKGARG----------RAFELG 256
            ||:||..|.              |..|| ..:||.|      |...|.|          .:|.:.
 Worm   206 HSSGGTIVD--------------ALGFS-KLIDPGVKLFQQMIVLSATGMFGFYDMVVDNSFAIV 255

  Fly   257 RNVGC-ESAEDS------TSLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAII 314
            ...|| ...:|.      ..:..|::.....|::...|..                     :.:.
 Worm   256 EKFGCYNGTKDDRPNANIAEMLDCMRQIDGREMLLMQRHM---------------------EEVD 299

  Fly   315 TQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERWLELAP--YLLFYRD 377
            .:|.|.|::...|.:                       .:|.:.|      |:.:|  ..|.|..
 Worm   300 DRDFRSVLRGAPFLE-----------------------SNGKIAD------LKKSPPSRNLLYGT 335

  Fly   378 TKTK-KDMDDYSRKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYV 441
            |:.: :::|..:     .||.....|.::...:.|.:.:.|..|       |........|..::
 Worm   336 TEHEFRNVDHMN-----PYISGIFLDFDNPVAVARYYDEQLMAN-------LETMINGDAAAIFI 388

  Fly   442 YDNPAEKGIAQVLAN-------RTDYDFGTVHGDD--YFLIFENFVRDVEMRPDEQIISRNFINM 497
            ..:.....:|...|:       :..|.|   |..|  ||:   ...|::..|||..|:...:..:
 Worm   389 CASTFSTAMANTGADVYLFETRQKPYSF---HVSDMQYFV---GIHREIYHRPDMDILDTFYSKL 447

  Fly   498 LADFASSDNGSLKYGECDFKDNVGSEKFQLLAIYID 533
            |.:|......|.::...|      .|:...|.:.:|
 Worm   448 LVNFTKMGVPSPEWAPLD------PERMNYLELKVD 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	123/556 (22%)
		Aes	<110..>243	CDD:223730	40/143 (28%)
cest-9.1	NP_001359584.1	Abhydrolase	19..498	CDD:389770	123/556 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157107
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740