Protein Alignment Est-6 and cest-9.1

DIOPT Version :10

• Sequence 1: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001359584.1
• Gene: cest-9.1 / 181383
• WormBaseID: WBGene00007692
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 556
• Identity: 123/556 - (22%)
• Similarity: 202/556 - (36%)
• Gaps: 149/556 - (26%)

  Fly    29 LVQLPQGKLRG-----RDNGSYYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQ 88
            ::|...|||||     .|....|.::|:|:|:||.|:|||..|: ..:.||.|.||:|...||:.
 Worm    20 VIQTSYGKLRGITVWSNDKNHRYMFKSVPFAKPPVGNLRFAKPQ-NPESWSGILDASKYSPACMS 83

  Fly    89 WDQFTPGANKLVGEEDCLTVSVYKPKNSKRNSFPVVAHIHGGAFMFGAAWQNGHENVMREGKFIL 153
            ....|....|.. .||||.::::..:....:..||:.:.||||:...:|       :|....|||
 Worm    84 NSSSTSTPQKHY-SEDCLYINIFTSEKCLNSKCPVIVYFHGGAYNLDSA-------IMFNDTFIL 140

  Fly   154 ----------VKISYRLGPLGFVSTGDRD-LPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVG 207
                      |..:.|||..|.:..|..| |..|..|.|...||.::...|..|||:.:.|..:|
 Worm   141 DRYAAEDVVFVIPAVRLGVFGQLYFGPSDLLSENLFLYDAVQALSFVHSEINYFGGDSKRVTAMG 205

  Fly   208 HSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWV------IQKGARG----------RAFELG 256
            ||:||..|.              |..|| ..:||.|      |...|.|          .:|.:.
 Worm   206 HSSGGTIVD--------------ALGFS-KLIDPGVKLFQQMIVLSATGMFGFYDMVVDNSFAIV 255

  Fly   257 RNVGC-ESAEDS------TSLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAII 314
            ...|| ...:|.      ..:..|::.....|::...|..                     :.:.
 Worm   256 EKFGCYNGTKDDRPNANIAEMLDCMRQIDGREMLLMQRHM---------------------EEVD 299

  Fly   315 TQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERWLELAP--YLLFYRD 377
            .:|.|.|::...|.:                       .:|.:.|      |:.:|  ..|.|..
 Worm   300 DRDFRSVLRGAPFLE-----------------------SNGKIAD------LKKSPPSRNLLYGT 335

  Fly   378 TKTK-KDMDDYSRKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYV 441
            |:.: :::|..:     .||.....|.::...:.|.:.:.|..|       |........|..::
 Worm   336 TEHEFRNVDHMN-----PYISGIFLDFDNPVAVARYYDEQLMAN-------LETMINGDAAAIFI 388

  Fly   442 YDNPAEKGIAQVLAN-------RTDYDFGTVHGDD--YFLIFENFVRDVEMRPDEQIISRNFINM 497
            ..:.....:|...|:       :..|.|   |..|  ||:   ...|::..|||..|:...:..:
 Worm   389 CASTFSTAMANTGADVYLFETRQKPYSF---HVSDMQYFV---GIHREIYHRPDMDILDTFYSKL 447

  Fly   498 LADFASSDNGSLKYGECDFKDNVGSEKFQLLAIYID 533
            |.:|......|.::...|      .|:...|.:.:|
 Worm   448 LVNFTKMGVPSPEWAPLD------PERMNYLELKVD 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	123/556 (22%)
cest-9.1	NP_001359584.1	alpha/beta hydrolases	19..484	CDD:473884	123/556 (22%)