Protein Alignment Est-6 and cest-16

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 152/599 - (25%)
• Similarity: 257/599 - (42%)
• Gaps: 124/599 - (20%)

  Fly     8 LIIVLSCLWLGSNASDTDDPLLVQLPQGKLRGR----DNGSYYSYESIPYAEPPTGDLRFEAPEP 68
            |:::|:.::..:|....:....|.:.||.:||.    |......:..:||||||.|:|||:.|..
 Worm     4 LLLLLTFIFSWANGQLLEKSRSVWVEQGLVRGNIYNIDGKHIQIFRGVPYAEPPIGELRFKPPVK 68

  Fly    69 YKQKWSDIFDATKTPVACLQW------DQFTPGANKLVGEEDCLTVSVYKP--KNSKRNSFPVVA 125
             |.:|.....|.:....|||:      |:|.. .|.....||||.::|:.|  .:.:..::|::.
 Worm    69 -KTRWHQELPAVEYGPPCLQFMDFHKNDKFAK-TNMDRQSEDCLYLNVFSPYDTDDESKTYPILV 131

  Fly   126 HIHGGAFMFGAAWQNGHE------NVMREGKFILVKISYRLGPLGFVS--TGDRDLPGNYGLKDQ 182
            .||||:|:.|:| ..|.:      |::.:| ...|.|:||||||||::  .||: |.||:|:.|.
 Worm   132 WIHGGSFLAGSA-DTGIDMEVIAANIVSKG-IAFVSINYRLGPLGFMNYQNGDK-LEGNFGIWDM 193

  Fly   183 RLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQKG 247
            .:||:||:.||..|.|:|..|.::|.|||||:..|..|......|...|...||:::..|.|.:.
 Worm   194 VMALQWIQSNIKQFNGDPTKVTVMGESAGGAASSLLALSPKTSGLLHQAIIMSGSSMAGWAIHRH 258

  Fly   248 ARGRAFELGRNVG---CES--AEDST------------------------SLK-KCLKSKPAS-E 281
            :: .|:.:...|.   ||.  .||.|                        ::| .||...... :
 Worm   259 SQ-PAYSVDNLVAYFRCEKWINEDDTKEVVGDEYQHLTHSVIRSALCNYQNVKINCLTDDMTQMD 322

  Fly   282 LVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAIITQ---DPRDVIKSG-----KFGQVPWAVSYVT 338
            .:..:||.|.||       ||:...:.|.:..:::   |...|..||     ...::|.......
 Worm   323 KMNCLRKELNFS-------SPLFRKALAAELGVSKMVVDGDLVPSSGVSLVRNNARIPIMTGVAR 380

  Fly   339 EDGGYNAALLLK-ERKSGIVIDDLNERWLELAPYLLF---YRDTKTKKDMDD------------Y 387
            ::.|:..|:... .::.|:...|:.|:     .|.:.   :.:|.::|..:.            |
 Worm   381 KEWGHKKAMFYNMHQRDGLKRSDVEEQ-----VYRIIDNSFHETASEKLANSTVQLIANATIVRY 440

  Fly   388 SRKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAEKGIAQ 452
            ......|:|.:|     ....||:|.:||.|....:..:..:...| .|.|.|.:|...:..|.:
 Worm   441 LETPNNEFIADQ-----VVGALQKLESDIEFVAPCEREVAAYVDKG-VPVYLYSFDYVPKSPILE 499

  Fly   453 VLANRTDYD-FGT------------------VHGDDYFLIF-ENFVRDVEMRP---DEQIISRNF 494
              :.|..|. |||                  .||.|:..|| :.:..:.|:.|   .|:.:|:..
 Worm   500 --SERKIYSLFGTKPVEMKRTEKSEILEKAAFHGLDHAFIFSKGYSSNFEISPYTKREETMSKIL 562

  Fly   495 INMLADFASSDNGS 508
            ..||.:|..:.:.|
 Worm   563 CTMLTNFVKNGDPS 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	149/578 (26%)
		Aes	<110..>243	CDD:223730	52/142 (37%)
cest-16	NP_741812.2	Abhydrolase	25..608	CDD:389770	149/578 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010