Protein Alignment Est-6 and glit-1

DIOPT Version :10

• Sequence 1: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_508807.1
• Gene: glit-1 / 180747
• WormBaseID: WBGene00018878
• Length: 730
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 148/599 - (24%)
• Similarity: 247/599 - (41%)
• Gaps: 162/599 - (27%)

  Fly    18 GSNASDTDDPLLVQLPQGKLRGRD----------------------------------NGSYYSY 48
            |.|.....|.::|:||.|.:.|::                                  |.:.:::
 Worm    45 GVNQGLNRDEVVVRLPLGDIVGKEVHLHNLPWTIHKDPTEELPKDGTHFDPNPLKPKNNITVFTF 109

  Fly    49 ESIPYAEPPTGDLRFEAPE-----PYKQKW-------SDIFDATKTPVACLQWDQFTPGANKLVG 101
            ..:|||||||...||:.|:     |.||.:       |...|..|:|      ..|.......:.
 Worm   110 LGVPYAEPPTSQRRFKPPQQLTVFPGKQPYLAFNYAASCAQDVEKSP------SPFVDHPYPFMV 168

  Fly   102 EEDCLTVSVYKPKNSK--RNSFPVVAHIHGGAFMFGAAWQNGHENVMREGKFILVKISYRLGPLG 164
            :||||.::::.|..||  :.::||:...|||.|..|:|.:.....:...| .::|.::||||..|
 Worm   169 DEDCLYLNIFSPDISKNAQTTYPVIVFFHGGNFQTGSANEWPAHGLASRG-MVVVTVNYRLGAFG 232

  Fly   165 FVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLAR 229
            |:|.||.: .|||||:||||||:::|.||.:|||:||.|.:|||.||.||:...|.......|.|
 Worm   233 FMSMGDSE-TGNYGLQDQRLALEFVKNNIVTFGGDPQAVTVVGHDAGAASIGFHMQSPYSRHLFR 296

  Fly   230 AAFSFSGNALDPWVIQKGARGRAF----ELGRNVGCESAEDSTSLKKCLKSKPASELVTAVRKFL 290
            :|.:.||..:. :....|....||    :|||..||..|. :.....|:.::...:::.|.|...
 Worm   297 SAATMSGAEVS-YHSYIGKTALAFNNTMKLGRYAGCTQAV-AQHRWDCILTRSTGDIIDATRNIP 359

  Fly   291 I----FSYVP-----FAPFSPVLEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAA 346
            |    :.::|     :.|.:|:....:||..          ::.....||..:....:||   :.
 Worm   360 IEYNRYLFMPTVDGKYLPGNPLWTLVNAPSG----------ETSIMSPVPMLIGMNAQDG---SE 411

  Fly   347 LLLKERKSG--IVIDDLNERWLELAPYLLFY---------RDTKTKKDMDDY--------SRKIK 392
            ::|::|:.|  ...:|::..:|:  .|.|.|         |:......:..|        :..||
 Worm   412 VVLEDRRLGEFSQFNDVDHEYLK--SYSLEYCYRHNYSMNREATADAILSKYTFWPDRAAAWAIK 474

  Fly   393 QEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAEKGIAQVLANR 457
            :.:|              :..||..:....|.|..||...| |..:.||
 Worm   475 ENFI--------------QFATDAYYTAPMQLSSHLHSSSG-SRVFQYV---------------- 508

  Fly   458 TDYDFGTVHGD--------------DYFLIF-ENFVRDVEMRP----------DEQIISRNFINM 497
            .:|:|...|.:              |.:|:| ..|:.| |:||          .::..||.|.|:
 Worm   509 NNYNFSRQHPNLLFIPDWMGVCRDCDLYLMFGYPFLPD-ELRPIGLRGINFTDTDRNASRTFSNI 572

  Fly   498 LADFASSDNGSLKY 511
            :..|:...|.:.::
 Worm   573 IRRFSYHQNPNFQF 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	145/588 (25%)
glit-1	NP_508807.1	alpha/beta hydrolases	98..629	CDD:473884	140/546 (26%)