Protein Alignment Est-6 and cest-2.2

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001256567.1
• Gene: cest-2.2 / 179917
• WormBaseID: WBGene00013874
• Length: 672
• Species: Caenorhabditis elegans
• Alignment Length: 530
• Identity: 123/530 - (23%)
• Similarity: 210/530 - (39%)
• Gaps: 131/530 - (24%)

  Fly    35 GKLRGRDNGSYYS---------YESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQWD 90
            |.:.||...:.||         :..:||.|||.|:|||..|.|.| .|..:.:|.:...||:. |
 Worm    27 GTIEGRTLTASYSPLGNQTGIVFFGVPYVEPPVGNLRFRKPRPPK-PWDGVLEAKEYKAACMS-D 89

  Fly    91 QFTPGANKLVG--EEDCLTVSVY------KPKNSKRNSFPVVAHIHGGAFMFGAAWQNGHE---- 143
            |.....|.:.|  .||||..:|:      :.||..     |:..||||.|:..:|.....|
 Worm    90 QKKTYKNGVGGPVSEDCLYANVFTNQYCLEHKNCS-----VMLTIHGGRFVIESASAYDPEIIIN 149

  Fly   144 NVMREGK-FILVKISYRLG--PLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLL 205
            |.:.:|: .::|..:||||  .||.::..::|.  |:||.|....::|.::.|.:|||:...:.:
 Worm   150 NFVGQGRNIVVVTFNYRLGLFGLGMLNGDNQDT--NFGLYDILEVVRWTRKEIKNFGGDKDRITM 212

  Fly   206 VGHSAGGASVHLQMLREDFGQLARAAFS---FSGNALDPWVIQKGA------RGRAFEL---GRN 258
            .|||||.              :..||||   .|...:...:|...:      :....||   .|.
 Worm   213 QGHSAGA--------------VFTAAFSTSPLSKGLIHQQIIMSASMSNLSKKSNVKELTVVARI 263

  Fly   259 VGCESAE------DSTSLKK---CLKSKPASELVTAVRKFLIFS---YVPFAPFSPVLEPSDAPD 311
            |||...|      .:..::|   ||:||.|.:::.| :.:::.:   |:.......:.: .|.||
 Worm   264 VGCLPDEHGFPKLSNVEVEKAYTCLRSKSAQQILDA-QLYMLRNTTYYIGQGHIDGIYQ-VDYPD 326

  Fly   312 AIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKER---------KSGIVIDDLNERWLE 367
            .:...:               ::..:....|...|.|:..|         |..|::.:|.|.
 Worm   327 NLYATN---------------SIYPINTMIGTTTAELMDSRYIVDPKNTGKKEILLQNLCEH--- 373

  Fly   368 LAPYLLFYRDTKTKKDMDDYSRKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKY 432
             ..|.|:       |:.:::|:|.:..|...:  |.:|..:....:...:...:...|.|.:
 Worm   374 -IGYELY-------KEPEEFSQKCRNFYKNGE--DAKSLGDDMEFYYGAIQLANVHSSKDTN--- 425

  Fly   433 GKSPAYAYVYDNPAEKGIAQVLANRTDYDFGTVHGDDYFLIF----ENFVRDVEMRPDEQIISRN 493
                .:.|.:|. .|.|.|.   .:.|......||:|:...|    .||      ...:.:|...
 Worm   426 ----VFVYSFDY-KEAGNAY---KKYDKSLSPKHGEDFAYAFGTNRGNF------STKDYVIEYI 476

  Fly   494 FINMLADFAS 503
            :..|.|||.:
 Worm   477 YSGMFADFVN 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	123/530 (23%)
		Aes	<110..>243	CDD:223730	40/148 (27%)
cest-2.2	NP_001256567.1	Abhydrolase	25..534	CDD:389770	123/530 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156994
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940