Protein Alignment Est-6 and cest-33

DIOPT Version :10

• Sequence 1: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_504621.1
• Gene: cest-33 / 179020
• WormBaseID: WBGene00017431
• Length: 554
• Species: Caenorhabditis elegans
• Alignment Length: 568
• Identity: 149/568 - (26%)
• Similarity: 239/568 - (42%)
• Gaps: 121/568 - (21%)

  Fly    35 GKLRG----RDNGSYYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQWDQFTPG 95
            |.:||    .|:.....|..||||:||.|:|||:.|... ..|::|.|..|...||:|    |.|
 Worm    22 GPVRGNIYKHDDVIVDGYLGIPYAKPPVGELRFKKPVTV-DVWTEIKDCYKYGPACVQ----TGG 81

  Fly    96 ANKLVG-------EEDCLTVSVYKPKNSK---RNSFPVVAHIHGGAFMFGA-----AWQNGHENV 145
            ..::.|       |..|||::|:.|:|:.   :|..||:.:||||.:...|     |:.......
 Worm    82 FEQIAGPRTPTPEEAGCLTLNVFTPRNASSEFKNGRPVMVYIHGGGYELCASSDFCAYSLSGTLP 146

  Fly   146 MREGKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSA 210
            :::  .::|.|:||||..||::|||...|||:||.||.|||||::::|:||||:|..|.:.|.||
 Worm   147 LKD--VVVVSINYRLGVFGFLTTGDNVCPGNFGLWDQTLALKWVQKHISSFGGDPNCVTVFGQSA 209

  Fly   211 GGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQKGARGRAFELGRNVGCESAE-------DST 268
            ||||..|..|......|.:.....||.|...:.|      ||.|....:..|.||       ||:
 Worm   210 GGASTDLLSLSPHSRDLFQRFIPISGTAHCDFAI------RASENQAKIFREFAEFHGFSGRDSS 268

  Fly   269 SLKKCLKSKPASEL--VTAVRKFLIFSYVPFAPFSPVLEPSDAP---DAIITQDPRDVIKSGKFG 328
            :|.|..:.:....|  |...:|    |...|..|.|.|:....|   |.:..:.|:..:.:|
 Worm   269 ALFKWYQEQSPETLSNVKGYKK----SISGFLTFIPNLDGDFFPKPLDELRKEAPKKQMMTG--- 326

  Fly   329 QVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERW------LELAPYLLFYRDTKTKKDMDDY 387
                    |||             ..|:::..:|..:      |.|.|..::.:|..:  :.|:.
 Worm   327 --------VTE-------------YEGLMLASMNPAFSPADVGLTLMPQGIYGKDVVS--NPDEI 368

  Fly   388 SRKIKQEYI-GNQRFD-IESYSELQRLFTDILFKNSTQESLDLHRKYGKSP-AYAYVYDNPAEKG 449
            .:...::|: |..:.| :....:|.....|..|.....::.....|:|... .|.:.|.||...|
 Worm   369 QKIFYEKYVEGVDKSDELAMRKKLCEALGDEFFNVGVIQAAKNAAKHGNEVYFYTFEYVNPDSFG 433

  Fly   450 IAQVLANRTDYD-----FGTVHGDDY-FLIFENFVRDVEMRPDEQIISRNFINMLADFA--SSDN 506
            :         :|     ...||..:. :|:.|......|...:::.:......:.::||  .:.|
 Worm   434 M---------WDGMMPFKAAVHCTELRYLLGEGVYSKFEPTEEDRKVMETTTTLFSNFAKYGNPN 489

  Fly   507 GS--------------------LKYGECDFKDNVGSEKFQLLAIYIDG 534
            |.                    :.|.:|:.:|.....:.|.|. .|||
 Worm   490 GKGATAEIWEKYSLNRPERHYRISYPKCEMRDVYHEGRIQFLE-KIDG 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	149/568 (26%)
cest-33	NP_504621.1	Esterase_lipase	16..521	CDD:238191	143/550 (26%)