Protein Alignment Est-6 and cest-24

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_504613.1
• Gene: cest-24 / 179017
• WormBaseID: WBGene00020891
• Length: 658
• Species: Caenorhabditis elegans
• Alignment Length: 630
• Identity: 161/630 - (25%)
• Similarity: 251/630 - (39%)
• Gaps: 174/630 - (27%)

  Fly    22 SDTDDPLLVQLPQGKLRG----RDNGSYYS-YESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATK 81
            |...:..:|::.||.|.|    ...|.... :..|||||||.|:|||:.|:|.| .|..|....|
 Worm    90 SGKSENAIVRVQQGLLEGFRVKTAKGDLCDVFHGIPYAEPPVGELRFQKPQPPK-AWEGIRKCNK 153

  Fly    82 TPVACLQ----WDQFTPGANKLVGEEDCLTVSVYKPKNSKRNSFPVVAHIHGGAFMFGAAWQNGH 142
            .|...:.    ||:..|.||:   .||||.::|:.||..:...:||:.:||||.::..:|.:...
 Worm   154 YPNRSIHKEMPWDKALPSANQ---SEDCLYLNVFAPKIREDKKYPVLFYIHGGGYVMDSAERYTA 215

  Fly   143 ENVMR---EGKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVL 204
            :|:.:   ..:.|:|...||||.|||:||||...||||||.|...|::|:..||:||||:|:|:.
 Worm   216 KNICKLLVSREIIVVTFHYRLGFLGFLSTGDDVCPGNYGLFDMLEAMRWVHANISSFGGDPENIT 280

  Fly   205 LVGHSAGGASVHLQMLREDFGQLARAAFS----FSGNALDPWV------IQKGARGRAFELGRNV 259
            |.|.|||.|:..|.    .|..|.:..|.    ..||:...|.      |::..:..|..||...
 Worm   281 LSGQSAGAAAADLL----SFSPLTKGLFKRKIVMGGNSYCHWATTSNHDIREYCKKWAKRLGWKP 341

  Fly   260 GCESA---EDSTSLKKCLKSKPASELVTAVRKFLIFSYVPF----APFSPVLEPSDAP-DAIITQ 316
            ....|   |:|..:.......|.|:|...    :.||...|    .|.:||::....| |..:.:
 Worm   342 QLNYANKREESVDIFNFFNGLPTSKLGMT----MFFSNTIFKECQLPLAPVIDGEILPHDLKVLR 402

  Fly   317 DPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLL----------------------KERKSGIVID 359
            :.::        .||..|.     ||...|||.                      |.|.|...|:
 Worm   403 ETQE--------HVPSLVG-----GGEYEALLFCAIGLLRGTEKEINSAIDVLSRKNRLSRSKIE 454

  Fly   360 DLNERWLELAPYLLFYRDTKTKKDMDDYSRKIKQEY--IGNQRF-------DIESYSE------- 408
            .:.|:....:|.|  ..|:|.:|..  :.:.|...:  .||.||       .:|.|..
 Worm   455 AMTEKVYGDSPAL--RADSKARKMF--FVQLISDIFANYGNYRFMRDCQQRGVECYGYSFDHQSK 515

  Fly   409 -----LQRLFTDILFKNSTQESLDLHRKYGKSPAYAYVYD----------NPAEKGIAQVLANRT 458
                 ||.:   :.|...|..|           ..:|::|          |..:|.::.:.|
 Worm   516 QMWGWLQHV---VPFTGGTHTS-----------ELSYLFDCNYMSAPLGMNKTDKVVSGMTA--- 563

  Fly   459 DY-----DFGTVHG-------------DDYFLIFENFVRDVEMRPDEQIISRNFINMLADFASSD 505
            ||     .|||.:|             ||      ..::.:.::|:.::.:..:...:.:|  .|
 Worm   564 DYFTNFVKFGTPNGPNSQLPKWERISPDD------EHMKLISIKPEPEMKTTVYGYRMQNF--ED 620

  Fly   506 NGSLKYGECD---------FKDNVGSEKFQLLAIYIDGCQNRQHV 541
            :..:.|.|.|         ||.::.|          .|..|..|:
 Worm   621 HLGMLYEEKDKSPFSPRGNFKPSIVS----------SGSDNSLHI 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	158/617 (26%)
		Aes	<110..>243	CDD:223730	53/139 (38%)
cest-24	NP_504613.1	COesterase	97..608	CDD:278561	149/562 (27%)
		Aes	<183..>285	CDD:223730	43/101 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010