Protein Alignment Est-6 and cest-6

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_501070.1
• Gene: cest-6 / 177459
• WormBaseID: WBGene00020688
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 557
• Identity: 126/557 - (22%)
• Similarity: 210/557 - (37%)
• Gaps: 156/557 - (28%)

  Fly     8 LIIVLSCLWLGSNASDTDDPLLVQLPQGKLRGRDNGSYYSYESIPYAEPPTGDLRFEAPEPYKQK 72
            ||.||..::   :|..:.:..::....|.:.|...|||.:::.||:|:||.|.|||:.|.. .:|
 Worm     7 LIFVLLIVY---SAYKSCEAGVITTSLGSINGNQIGSYQTFKKIPFAKPPIGKLRFQKPMA-AEK 67

  Fly    73 WSDIFDATKTPVACLQWDQFTPGANKLVGEEDCLTVSVYKPKN--SKRNSFPVVAHIHGGAFMFG 135
            |..|.:||:...||:.....:....|.: :||||.::::....  |.:|. .||.::|||..::.
 Worm    68 WEGILNATEYGPACMSNSSTSKSPQKWI-DEDCLHINIFTTDTCLSSKNC-SVVFYVHGGELVYD 130

  Fly   136 AAWQNGHENVMREGKF----------ILVKISYRLGPLGFVSTGDRDL-PGNYGLKDQRLALKWI 189
            :|       ||.|.|:          |||..::|||........|::: |.|..|.|..|||:::
 Worm   131 SA-------VMFEDKYLFDTFSSRDVILVIPAFRLGLFSHFVVEDQNVAPNNLALYDILLALEFV 188

  Fly   190 KQNIASFGGEPQNVLLVGHSAGGASVHLQM----LREDFGQLARAAFSFSGNALD--PWVIQKGA 248
            |..|.:|||....|...|||.||..|.:..    :..|.....|.....|.|..|  .:.|:|..
 Worm   189 KSEIHNFGGSSDRVTAFGHSYGGHVVSVMAFSTEINTDLSYFQRVICMSSVNVWDSLEFEIEKTM 253

  Fly   249 RGRAFELGRNVGCE----------SAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPV 303
            |...:     ..|.          |.|..:.:.:||:...:.||:...|..
 Worm   254 RFIQY-----ANCSVPQDLKSRMTSFEQDSYMMECLQDIDSMELLRIQRSL-------------- 299

  Fly   304 LEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGG---YNAALLLKERKSGIVIDDLNER- 364
                                               ||.|   |:..:|.:.....:::.|..|:
 Worm   300 -----------------------------------EDEGHPIYSGLVLREPLIQNVLVQDFYEKP 329

  Fly   365 ----------WLELAPYLLFYRDTKT-----KKDMDDYSRKIKQEYIGNQRFDIESYSELQRLFT 414
                      :.||..:..::...:|     .|:.||..|. .::|   .|||:..::
 Worm   330 KNIPTLTGCTYKELDKFHAYHNIVETLGYENYKECDDKYRD-DRKY---GRFDLNKHA------- 383

  Fly   415 DILFKNSTQESLDLHRKYGKS-PAYAYVYDNPAEKGIAQVLANRTDYDFGTVHGDD--YFLIFEN 476
            |..|....|..|.:.::..|. |.|.|.|..|....                |.||  |.:....
 Worm   384 DETFGILAQTKLKVDKQLDKGIPTYFYEYSYPKHPS----------------HTDDLSYIMGVHA 432

  Fly   477 FVRDVEMRPDEQIISRNFINMLADFASSDNGSLKYGE 513
            |.:|    .:|..:::::..|..:|       :|:||
 Worm   433 FEKD----ENEIHLAKSYQEMFMNF-------VKFGE 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	121/536 (23%)
		Aes	<110..>243	CDD:223730	43/151 (28%)
cest-6	NP_501070.1	Abhydrolase	25..500	CDD:389770	121/536 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156874
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740