Protein Alignment Est-6 and cest-12

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_499576.4
• Gene: cest-12 / 176642
• WormBaseID: WBGene00013540
• Length: 850
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 114/540 - (21%)
• Similarity: 185/540 - (34%)
• Gaps: 164/540 - (30%)

  Fly    11 VLSCLWLGSNASDTDDPLLVQLPQGKLRGR------DNGSYYS-----YESIPYAEPPTGDLRFE 64
            |.:..:...|.:...:.:.|...||.::||      |....||     :..|||.:.|.|:||.:
 Worm    18 VSNAQYQNQNQNQQSNYVTVSCSQGSVQGRQVNLGNDQSQLYSGQANAFTGIPYCQAPVGNLRLQ 82

  Fly    65 APEPYKQKWSDIFDATKTPVACLQWDQFTPGANKLVGEEDCLTVSVYKPKNSKRN-SFPVVAHIH 128
            .|:|..|..:.:.|||.....|.|.:...|      ..||||.::||.|:....| :..|:..|.
 Worm    83 PPQPLNQFNTTLHDATYFRPKCPQLNAGGP------TNEDCLYLNVYTPQAGNTNANLSVLVLID 141

  Fly   129 G-GAFMFGAAWQNGHENVMR---EGKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWI 189
            | ..|..|...||..:.::.   :.:.::|.:.||:|.|||.:|....:..|.|:.||..|::||
 Worm   142 GSNGFSNGGCDQNQEKGIISNLVQRQIVVVTMQYRIGALGFFTTYTNSVQSNLGMLDQVQAMRWI 206

  Fly   190 KQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQKGARGRAFE 254
            |..|.:|||.|..:.:.|...|..:|                   |.:.|.|
 Worm   207 KTEIVNFGGNPNQITVAGQDDGACAV-------------------SAHCLSP------------- 239

  Fly   255 LGRNVGCESAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAIITQDPR 319
            :.:|:..::...|.|:..|....||               ||..|...|..|....|...|
 Worm   240 MSQNLFNQAIVQSGSVYSCYNPTPA---------------VPTNPQVQVTTPRPMYDQSNT---- 285

  Fly   320 DVIKSGKFGQVPWAVSY------VTEDGGYNAALLLKERKSGIVIDDLNERWLELAPYLLFYRDT 378
                  .:|...:..:|      :|....||:|               |.::
 Worm   286 ------GYGNAGYQNNYGYQPQPITSTSSYNSA---------------NAQY------------- 316

  Fly   379 KTKKDMDDYSRKIKQ--------EYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKS 435
                  ||.|:::.|        ::...|..:|::           ..||.|.:.....:..|.:
 Worm   317 ------DDPSQQLAQTLCNISPDQWNNGQTQNIQN-----------CMKNYTVDFFVNQQPGGPN 364

  Fly   436 PAYAYVYDNPAEKGIAQVLANR---------------TDYDFGTVHG---------DDYFLIF-- 474
            ..:..|.|.....|....|..|               .||.|..::.         ||:...|
 Worm   365 ATWMIVRDTSFLPGSIDSLTTRRPNIPIIIGTVQDEDADYAFKLINTGKGSDPNNLDDWIFDFAR 429

  Fly   475 ENFVRDVEMRPDEQIISRNF 494
            :|.:...:......|||.|:
 Worm   430 KNKLNQTQANQVSNIISNNY 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	112/522 (21%)
		Aes	<110..>243	CDD:223730	38/137 (28%)
cest-12	NP_499576.4	Abhydrolase	37..>400	CDD:389770	101/470 (21%)
		Abhydrolase	<678..774	CDD:389770

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000