Protein Alignment Est-6 and cest-25

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_497609.1
• Gene: cest-25 / 175390
• WormBaseID: WBGene00022178
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 496
• Identity: 129/496 - (26%)
• Similarity: 208/496 - (41%)
• Gaps: 112/496 - (22%)

  Fly    47 SYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQWDQ-FTPGANKLVGEEDCLTVSV 110
            :::.||||.||.|:|||..|:|: :||:::.:........:|.|. .:|..:.  ..||.||:::
 Worm    41 AFQGIPYAAPPIGNLRFALPQPH-EKWTEVRETKSFGARGIQKDHVLSPKTSP--QSEDNLTLNI 102

  Fly   111 YKPKNSKRN--SFPVVAHIHGGAFMFGAAWQNGHENVMRE---GKFILVKISYRLGPLGFVSTGD 170
            :.|..:.:|  .|||:.:||||.|:..:|.:.|..::.:.   ...::|.|.||||.|||.:|||
 Worm   103 FTPVWTPKNETGFPVILYIHGGGFVSDSAHKYGDMSICQHLVTKDVVVVTIQYRLGFLGFWTTGD 167

  Fly   171 RDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFS 235
            ..:|.|..|.|...||||:|:||..|.|:|.|:.|:|.|||||||....:......|.:......
 Worm   168 SSIPDNVALHDMVFALKWVKENIGLFNGDPNNITLMGQSAGGASVDFLSISPVSRDLFQKVIPMG 232

  Fly   236 GNALDPWVIQ----KGARGRAFELGRNVGCESAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVP 296
            |||...|.|.    ...|.||.|:|...|..:.:....|::.    ||.:..:|:..
 Worm   233 GNASCSWAIHPRPLNACRNRAQEIGVFDGMNTLDWVEKLREL----PADKFASALNM-------- 285

  Fly   297 FAPFSPVLEPSDAPDAIITQDPRDVIKSGKFGQ--VPWAVSYVTEDGGYNAALLLKERKSGIVID 359
                          :|:.|:...:::...|:..  :|..|..:.::......||...:..|:|
 Worm   286 --------------EAVDTKTDPELLIGPKYDNLFIPRPVMELRKEAPMKPRLLGCAKSEGLV-- 334

  Fly   360 DLNERWLELAPYLLFYRDTK-----TKKDMD-------------DYSRKIKQEY--IGNQRFDIE 404
                       :..|..:||     .::|:.             ||..|..::.  ||..    .
 Worm   335 -----------FAFFGLNTKHPLHAVQQDVSAILSEKLFPLKARDYQEKALEKLIEIGTD----H 384

  Fly   405 SYSELQRLFTDI-----LFKNSTQESLDLHRKYGKSPAYAYVYD--NPAEKG------------- 449
            |..|.||...|:     |.....|..||:......:|.|.|.:|  ||...|
 Worm   385 SKEEWQRAMVDLKGDSFLNVGIQQNVLDVLETQPSTPIYMYSFDYCNPKAYGIMGFKLPFKDATH 449

  Fly   450 ---IAQVLANR--TDYDFGTVHGDDYFLI------FENFVR 479
               |:.|:.|.  ..:||   :.:||.:|      :.||.:
 Worm   450 CTDISYVVGNHIVNSFDF---NEEDYKMIEITTRLWTNFAK 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	129/496 (26%)
		Aes	<110..>243	CDD:223730	52/137 (38%)
cest-25	NP_497609.1	COesterase	18..536	CDD:365897	129/496 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D222591at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820