Protein Alignment Est-6 and cest-27

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_871861.2
• Gene: cest-27 / 171610
• WormBaseID: WBGene00018958
• Length: 561
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 150/553 - (27%)
• Similarity: 244/553 - (44%)
• Gaps: 107/553 - (19%)

  Fly    35 GKLRG----RDNGSYY-SYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQWDQFTP 94
            |.::|    :::||.. .:..|||||||.|.|||:.|..:: ||::       |:.|:::...:|
 Worm    33 GPIKGVGYEQEDGSVVEGFLGIPYAEPPIGALRFKKPVAHR-KWTE-------PLDCVRFGPRSP 89

  Fly    95 GANKLVG---------EEDCLTVSVYKPK---NSKRNSFPVVAHIHGGAFMFGAAWQNGHENVMR 147
            ..::|:|         ||.||:::|:.||   |...:.|||:..||||.|...::...|..::.|
 Worm    90 QNDELLGQFVNTVGKSEEHCLSLNVFTPKWESNEWPDGFPVMVFIHGGGFAVHSSSNYGCASIAR 154

  Fly   148 E---GKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHS 209
            .   ...::|.|:||||.|||.:|||....||.||.||..||:|:::||.||.|:|.||.:.|.|
 Worm   155 NLCTKDVVVVTINYRLGVLGFFTTGDEVCRGNLGLWDQTAALEWVQENIQSFRGDPDNVTIFGQS 219

  Fly   210 AGGASVHLQMLREDFGQLARAAFSFSGNALDPWVI----QKGARGRAFELGRNVGCESAE-DSTS 269
            ||||||.|..|......|...|...:||....:.:    |:....|  |..|.:|.|..: ||..
 Worm   220 AGGASVDLLCLSPHSRGLFNRAIPMAGNGECDFAMRTSEQQAQLSR--EFARYLGWEGDDNDSED 282

  Fly   270 LKKCLKSKPASELVTAVRKFLIFSY-----VPFAP-----FSPVLEP-----SDAPD-AIITQDP 318
            |.:.:..:|..::...:.....|.:     :.|.|     |.|  :|     .:||. .|:|...
 Worm   283 LLQFIDQQPLYKIEMGINPKRGFKHSQAGSLYFVPNFDGDFFP--KPLNQLRKEAPKMQIMTGTT 345

  Fly   319 RDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERWLELAPYLLFYRDTKTKKD 383
            :   ..|.|.....|:|...|........:.||...|...||:    |::. |..:::....|
 Worm   346 K---YEGLFFIALGALSKNPEGIKKFMGRIFKECDYGERADDV----LQMV-YDFYFKGVHPK-- 400

  Fly   384 MDDYSRKIKQ--EYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPA 446
              |:.:.:.|  ::||:...:..:| .|..:.||:           .|..|    .|.:.|.|.|
 Worm   401 --DHEKNMHQIVKFIGDYSINYGTY-RLANIMTDL-----------QHDVY----FYQFDYHNSA 447

  Fly   447 EKGIAQVLANRTDYDFGTVHGDD--YFL---IFENFVRDVEMRPDE------QIISRNFINMLAD 500
            ..|:.:.|..    ..|:.|..:  |.|   |...|      ||::      .:::..|.| .|.
 Worm   448 GFGVFRWLLP----FLGSTHCTEMRYVLGKGIISKF------RPNDNDKKMLHVMTTYFTN-FAK 501

  Fly   501 FASSDNGSLKYGECDFKDNVGSEKFQLLAIYID 533
            :.:.:..:.:.||....|:  :..|:...|.:|
 Worm   502 YGNPNGENQETGEWQKHDS--AHPFRHFKIDLD 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	150/553 (27%)
		Aes	<110..>243	CDD:223730	57/138 (41%)
cest-27	NP_871861.2	COesterase	29..541	CDD:278561	150/553 (27%)
		Aes	<114..>283	CDD:223730	65/170 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157208
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840