Protein Alignment Est-6 and Gli

DIOPT Version :10

• Sequence 1: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_061510245.1
• Gene: Gli / 1277780
• VectorBaseID: AGAMI1_001484
• Length: 973
• Species: Anopheles gambiae
• Alignment Length: 547
• Identity: 156/547 - (28%)
• Similarity: 246/547 - (44%)
• Gaps: 85/547 - (15%)

  Fly    23 DTDDPLLVQLPQGKLRGRDNGSYYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACL 87
            |..||..:..|......|..|...::..||||.|||.:.||:.|..:: .| .:..|.....||.
Mosquito   160 DNPDPKNLYRPWHSNVDRIMGKCSTFLGIPYALPPTHEGRFKPPRQHR-GW-QLVQAVDYGPACP 222

  Fly    88 QWDQFTPGANKLVG--EEDCLTVSVYKPKNSK--RNSFPVVAHIHGGAFMFGAAWQNGHENVMRE 148
            |..|:| ||.|.:.  :||||.::::.|....  ...:||:.:||||.|:.||:  |.....|..
Mosquito   223 QPVQYT-GATKGIRDMDEDCLYLNIFSPNTQAGVAQRYPVMIYIHGGEFVRGAS--NTFPGHMLA 284

  Fly   149 GKF--ILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAG 211
            ..:  ::|..:||||.|||:||||.:.|||||:.||.:|::|:.:||.||.|:..::.|.|..||
Mosquito   285 AFYDVVVVTFNYRLGALGFLSTGDENSPGNYGILDQIMAVRWVYENIESFNGDRNSITLFGPGAG 349

  Fly   212 GASVHLQMLREDFGQLARAAFSFSGNALDPW--VIQK-GARGRAFELGRNVGCESAEDSTSLKKC 273
            |||..|.|:......:.......||:||..|  ::.| .|:..:....:|||| |.|.|..:..|
Mosquito   350 GASAGLLMVAPQTKDIVTRVIGQSGSALADWALIVDKWRAQNTSRVFAQNVGC-SIETSWKMVNC 413

  Fly   274 LKSKPAS-ELVTAVRKFLIFSYVPFAPFSPVLE-----PSDA--------PDAIITQDPRDVIKS 324
            :::..:| ||..|  :|.  .:|...|:.||||     |.|:        ....:.:.|..:|:.
Mosquito   414 MRNGRSSYELGNA--EFP--PHVGLFPWGPVLENNFTFPGDSWYEGWSERDWHFLAETPESLIRR 474

  Fly   325 GKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERWLE--LAPYLLFYRDTKTKKDMDDY 387
            ..|.:....:|.||..   .||.::...||.....:::||:.:  :...:|.|..|   .:::..
Mosquito   475 RHFNRGLHYMSGVTLQ---EAAFVITGNKSLAPYFEVDERFFDQKVRELVLRYNYT---LNLNGT 533

  Fly   388 SRKIKQEYI-----GNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAE 447
            ...||..|.     .|..|..|.|.   .|.:|.|::..|.:.:.|..:. ..|.|:||.:...|
Mosquito   534 YEAIKYMYTYWPDPKNTTFIREQYI---NLLSDFLYRAPTDKLIKLLVEQ-NVPVYSYVMNTTIE 594

  Fly   448 KGIAQVLANRTDYDFGTVHGDDYFLIFENFVRDVEMRP------------DEQIISRNFINMLAD 500
             |:......:..:|.     :.|.|....|: |||..|            :::.:|..|:...:|
Mosquito   595 -GLKLAEWCKVPHDI-----EHYLLAGAPFM-DVEFFPRRERFDRLMWTDNDRNMSHFFMKTYSD 652

  Fly   501 FA----------------SSDNGSLKY 511
            ||                .:.||.|||
Mosquito   653 FARHGNPTPTQVLGLYFEKARNGELKY 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	153/541 (28%)
Gli	XP_061510245.1	None