Protein Alignment Est-6 and Ache

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_036020624.1
• Gene: Ache / 11423
• MGIID: 87876
• Length: 616
• Species: Mus musculus
• Alignment Length: 564
• Identity: 166/564 - (29%)
• Similarity: 249/564 - (44%)
• Gaps: 135/564 - (23%)

  Fly     8 LIIVLSCLWLGSNASDTDDP-LLVQLPQGKLRG----RDNGSYYSYESIPYAEPPTGDLRFEAPE 67
            |.::||.|..|:.|...:|| |||::..|:|||    ...|...::..||:||||.|..||..||
Mouse    18 LFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPE 82

  Fly    68 PYKQKWSDIFDATKTPVACLQW-DQFTPG--------ANKLVGEEDCLTVSVYKPKNSKRNSFPV 123
            | |:.||.:.|||.....|.|: |...||        .|:.: .||||.::|:.|.....:..||
Mouse    83 P-KRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNREL-SEDCLYLNVWTPYPRPASPTPV 145

  Fly   124 VAHIHGGAFMFGAAWQNGHENVMREGKF-------ILVKISYRLGPLGFVS-TGDRDLPGNYGLK 180
            :..|:||.|..|||..:     :.:|:|       :||.::||:|..||:: .|.|:.|||.||.
Mouse   146 LIWIYGGGFYSGAASLD-----VYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLL 205

  Fly   181 DQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPW-VI 244
            ||||||:|:::|||:|||:|.:|.|.|.|||.|||.:.:|......|...|...||....|| .:
Mouse   206 DQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATV 270

  Fly   245 QKG-ARGRAFELGRNVGCE---SAEDSTSLKKCLKSKPASELVT----AVRKFLIFSYVPFAPFS 301
            ..| ||.||..|.|.|||.   :..:.|.|..||:::||.:||.    .:.:..||.:    .|.
Mouse   271 SAGEARRRATLLARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRF----SFV 331

  Fly   302 PVLEP---SDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNE 363
            ||::.   ||.|:|:        |.:|.|..:...|..|.::|.
Mouse   332 PVVDGDFLSDTPEAL--------INTGDFQDLQVLVGVVKDEGS--------------------- 367

  Fly   364 RWLELAPYLLFYRDTKTKKDMDDYSRKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDL 428
                   |.|.|......||.:  |...:.:::...|..:...|:|            ..|::.|
Mouse   368 -------YFLVYGVPGFSKDNE--SLISRAQFLAGVRIGVPQASDL------------AAEAVVL 411

  Fly   429 HRK---YGKSPAY------AYVYDNPAEKGIAQVLANRTDYDFGTVHGDDYFLIFEN-------- 476
            |..   :.:.|.:      |.|.|:.....:|| ||.|.......|    |..|||:
Mouse   412 HYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQ-LAGRLAAQGARV----YAYIFEHRASTLTWP 471

  Fly   477 ------------FVRDVEMRP------DEQIISRNFINMLADFA 502
                        |:..:.:.|      :|:|.::..:....:||
Mouse   472 LWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFA 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	157/542 (29%)
		Aes	<110..>243	CDD:223730	57/141 (40%)
Ache	XP_036020624.1	COesterase	37..563	CDD:395084	159/545 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832782
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840