Protein Alignment Est-6 and nlgn4x

DIOPT Version :10

• Sequence 1: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_017946613.1
• Gene: nlgn4x / 100329189
• XenbaseID: XB-GENE-6036018
• Length: 833
• Species: Xenopus tropicalis
• Alignment Length: 566
• Identity: 158/566 - (27%)
• Similarity: 238/566 - (42%)
• Gaps: 120/566 - (21%)

  Fly     6 LGLIIVLSC--------LWLGSNA-------SDTDDPLLVQLPQGKLRGRDN-------GSYYSY 48
            |.||....|        ||:.:.|       .....| :|....||:||...       |....|
 Frog    10 LPLIFTPVCVLVNSNLLLWIAALAVRFTIVDCQAQHP-IVPTNYGKIRGTRTPLPIEILGPVEQY 73

  Fly    49 ESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQW-DQ-----------FTPGANKLVG 101
            ..:|||.||||:.||:.||| ...|:.|.:||:....|.|: |:           ||...:.:|.
 Frog    74 LGVPYASPPTGERRFQPPEP-PSSWTGIKNATQFAPVCPQFLDERSLLNDMLPIWFTANLDTVVS 137

  Fly   102 -----EEDCLTVSVYKP--------------KNSKR----------NSFPVVAHIHGGAFMFGAA 137
                 .||||.:::|.|              .|:.|          |..||:.:||||::|.|..
 Frog   138 YVQDQNEDCLYLNIYVPTEDGATTKKQADDIANNDRGEDEDIHDPNNKKPVMVYIHGGSYMEGTG 202

  Fly   138 WQNGHENVMREGKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQN 202
            .......:...|..|::.::||||.|||:||||:...|||||.||..||:||::||.:|||:|:.
 Frog   203 NMIDGSILASHGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIEENIGAFGGDPKR 267

  Fly   203 VLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQKGARGRAFELGRNVGCESAEDS 267
            |.:.|..||.:.|.|..|......|.:.|...||.||..|.:..........|...|||:.. |:
 Frog   268 VTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCDML-DT 331

  Fly   268 TSLKKCLKSKPASELVTAVRKFLIFSYVP---FAPFSPVLEPSDAPDAIITQDPRDVIKSGKFGQ 329
            ..|.:||:.|...||:..       |..|   ...|.||::....||     ||:.:::.|:|
 Frog   332 IDLVECLRDKNYKELIQQ-------SITPATYHIAFGPVIDGDVIPD-----DPQILMEQGEF-- 382

  Fly   330 VPWAVSY-----VTEDGGYNAALLLKERKSGIVIDDLNERWLELAPYLLFY---RDT--KTKKDM 384
                ::|     |.:..|......:.:.:.|:.:.|.:.........|..|   :||  :|.|.|
 Frog   383 ----LNYDIMLGVNQGEGLKFVDGMVDNEDGVSLSDFDFSVSNFVDNLYGYPEGKDTLRETIKFM 443

  Fly   385 -DDYSRKIKQEYIGNQRFDIESYSELQRLFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAEK 448
             .|::.|...|   .:|      ..|..||||..:......:.|||.:|| ||.|.|.:.:..:.
 Frog   444 YTDWADKENPE---TRR------KTLVALFTDHQWVAPAVATADLHARYG-SPTYFYAFYHHCQS 498

  Fly   449 GIAQVLANRTDYDFGTVHGDDYFLIFENFVRDVEMRPDEQIISRNF 494
            .:....|:       :.|||:...:|     .:.|....::.:.||
 Frog   499 EMKPTWAD-------SAHGDEVPYVF-----GIPMIGPTELFNCNF 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	150/528 (28%)
nlgn4x	XP_017946613.1	COesterase	46..610	CDD:395084	151/530 (28%)