Protein Alignment Est-6 and nlgn1

DIOPT Version :9

• Sequence 1: NP_001261749.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_017949302.2
• Gene: nlgn1 / 100329186
• XenbaseID: XB-GENE-6041753
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 583
• Identity: 150/583 - (25%)
• Similarity: 223/583 - (38%)
• Gaps: 158/583 - (27%)

  Fly    12 LSCLW-----------------------------LGSNASDTDDPLLVQLPQGKLRGRDN----- 42
            |:|||                             :.|...|..|| :|....||:||...
 Frog     9 LNCLWRVTWLRFLPMGLDSTFVLCVFGFLLHIATVRSQKLDDVDP-VVLTTYGKVRGFKKELNNE 72

  Fly    43 --GSYYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQ--------------WDQ 91
              |....:..:|||.||.|:.||:.||| ...|.||.::|:....|.|              |
 Frog    73 ILGPVVQFLGVPYAAPPIGERRFQPPEP-PTMWGDIKNSTQFAPVCPQNIVGGRLPEVMLPVW-- 134

  Fly    92 FTPGANKLVG-----EEDCLTVSVYKP-KNSKRNS------------------------------ 120
            ||...:.:..     .||||.:::|.| ::.||.|
 Frog   135 FTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICRKEGPLTKKQTDDLGDNE 199

  Fly   121 -------------FPVVAHIHGGAFMFGAAWQNGHENVMREGKFILVKISYRLGPLGFVSTGDRD 172
                         .||:.:||||::|.|.........:...|..|::.::||||.|||:||||:.
 Frog   200 GAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNVFDGSVLASYGNVIVITVNYRLGVLGFLSTGDQA 264

  Fly   173 LPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQ----------L 227
            ..|||||.|...||:|..:||..|||:|..:.:.|..||.:.|:|..| ..:.:          |
 Frog   265 SKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGASCVNLLTL-SHYSEGNRWSNSTKGL 328

  Fly   228 ARAAFSFSGNALDPWVIQKGARGRAFELGRNVGCESAEDSTSLKKCLKSKPASELV----TAVRK 288
            .:.|.:.||.||..|.:.......|..|...||| :..||..|.:||:.||..|||    ..||.
 Frog   329 FQRAIAQSGTALSSWAVSFQPAKYARILATKVGC-NMSDSGELVECLQKKPYRELVDQDIQPVRY 392

  Fly   289 FLIFSYVPFAPFSPVLEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSY-----VTEDGGYNAALL 348
            .:        .|.||::....||     ||:.:::.|:|      ::|     |.:..|......
 Frog   393 HI--------AFGPVIDGDVIPD-----DPQVLMEQGEF------LNYDIMLGVNQGEGLKFVES 438

  Fly   349 LKERKSGIVIDDLNERWLELAPYLLFYRDTKTKKDMDDYSRKIKQEYIG-NQRFDIESYSE-LQR 411
            ..:.:.|:...|.:.........|..|.:.|     |.....||..|.. ..|.:.|:..: |..
 Frog   439 TVDHEDGVSSSDFDFAVSNFVDNLYGYTEGK-----DILRETIKFMYTDWADRNNPETRRKTLLA 498

  Fly   412 LFTDILFKNSTQESLDLHRKYGKSPAYAYVYDNPAEKGIAQVLANRTDYDFGTVHGDDYFLIF 474
            ||||..:......:.|||..:| ||.|.|.:.:..:.......|:.:       |||:...:|
 Frog   499 LFTDHQWVAPAVATADLHSNFG-SPTYFYAFYHHCQTDQVPAWADAS-------HGDEIPYVF 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_001261749.1	Esterase_lipase	29..537	CDD:238191	142/537 (26%)
		Aes	<110..>243	CDD:223730	53/186 (28%)
nlgn1	XP_017949302.2	COesterase	52..646	CDD:395084	144/540 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910