Protein Alignment Est-6 and ces2

DIOPT Version :10

• Sequence 1: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001120019.1
• Gene: ces2 / 100144981
• XenbaseID: XB-GENE-6467140
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 556
• Identity: 156/556 - (28%)
• Similarity: 244/556 - (43%)
• Gaps: 123/556 - (22%)

  Fly     9 IIVLSCLWLGSNASDTDDPLLVQLPQGKLRGRDNGS------YYSYESIPYAEPPTGDLRFEAPE 67
            :::|.|..|....::...|||: ...|:|.|:..|:      .:.:..:|:|:||.|.||||||:
 Frog     7 VLLLCCATLEIYGTEDARPLLM-TKYGQLLGKTVGAKETDRLVHVFMGVPFAKPPIGPLRFEAPQ 70

  Fly    68 PYKQKWSDIFDATKTPVACLQWDQFTPGANKLVGE----------------EDCLTVSVYKPKNS 116
            | .:.||.:.:||.....|||        :|.|.|                ||||.::|:.|.:.
 Frog    71 P-PEPWSSVREATAPSPMCLQ--------DKEVMELLADFFKAKFDFSRVSEDCLYLNVFTPADK 126

  Fly   117 KRN-SFPVVAHIH------GGAFMFGAAWQNGHENVMREGKFILVKISYRLGPLGFVSTGDRDLP 174
            ..| ..||:..||      |||.||..:..:.:|||      ::|.|.||||.:||:||||:::.
 Frog   127 GENPGLPVMVFIHGGGLAIGGASMFEGSALSAYENV------VVVSIQYRLGIMGFLSTGDKEVR 185

  Fly   175 GNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNAL 239
            ||:|..||..||:|::.||..|||:||:|.:.|.||||.||...:|......|...|.:.||.|:
 Frog   186 GNFGFLDQVAALQWVRDNIKDFGGDPQSVTIFGESAGGLSVSALVLSPLSEGLFHRAIAESGVAI 250

  Fly   240 DPWVIQKGARG--RAFELGRNVGCESAEDSTSLKKCLKSKPASEL--VTAVRKFLIFSYVPFAPF 300
            .|.:.......  ...::..||...|..|   |..|||:|...|:  :||..:::||..|....|
 Frog   251 LPGLTASKTEEILPLLDMVINVSSCSVSD---LVGCLKNKTEDEIIEITAAMRYVIFPAVVDGVF 312

  Fly   301 SPVLEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERW 365
            .|  :|::           :::.:.:...||:.:       |.|                 |..:
 Frog   313 LP--KPAE-----------EILAAKESHPVPFLI-------GIN-----------------NHEF 340

  Fly   366 LELAPYLL---FYRDTKTKKD-------------MDDYSRKIKQEYIGNQRFDIESYSELQRLFT 414
            ..:.|..|   .||:...|||             :......|.:||.|:.....|..:....|..
 Frog   341 GSMLPVTLNITGYREGMEKKDIQAILGALPLLNTVSSVIPFIMEEYFGDTNDPKELRNNFLDLAG 405

  Fly   415 DILFKNSTQESLDLHRKYGKSPAYAYVYDN-PAEKGIAQVLANRTDYDFGTV-HGDD-YFLIFEN 476
            ||:|......:...||..| .|.|.|.:.: |:       |...:..||... |||: ||:....
 Frog   406 DIIFVIPALRTAKYHRDSG-FPVYFYEFQHRPS-------LYADSKEDFVKADHGDELYFVGGGP 462

  Fly   477 FVRDVEM-----RPDEQIISRNFINMLADFASSDNG 507
            |:::..:     ..:|:|:|:..:...|:||.  ||
 Frog   463 FLKNGILFKSNGTEEEKILSKTIMKYWANFAR--NG 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	151/536 (28%)
ces2	NP_001120019.1	COesterase	25..536	CDD:395084	153/538 (28%)