DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH2 and ACA7

DIOPT Version :9

Sequence 1:	NP_648555.1	Gene:	CAH2 / 39390	FlyBaseID:	FBgn0027843	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_172287.1	Gene:	ACA7 / 837326	AraportID:	AT1G08080	Length:	275	Species:	Arabidopsis thaliana

Alignment Length:	274	Identity:	76/274 - (27%)
Similarity:	125/274 - (45%)	Gaps:	58/274 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QDFGYE--GRHGPEHWSE---DYARC-SGKHQSPINI--DQVSAVEKKFPKLEFFNFKVVPDNLQ 82
            ::|.|:  ...|||.|.|   ::..| .|:.||||::  ::|:.|.    .|...|....|.|..
plant    38 REFNYKKNDEKGPERWGELKPEWEMCGKGEMQSPIDLMNERVNIVS----HLGRLNRDYNPSNAT 98

  Fly    83 MTNNGHTVLVKMSYNEDEIPSVRGGPLAEKTPLGYQFEQFHFHWGENDTIGSEDLINNRAYPAEL 147
            :.|.||.:::|.   ||...:::..        |:::|....||..    .||..||.|.:..||
plant    99 LKNRGHDIMLKF---EDGAGTIKIN--------GFEYELQQLHWHS----PSEHTINGRRFALEL 148

  Fly   148 HVVLRNLEYPDFASALDKDHGIAVMAFFFQVGDKST------GGYEGFTNLLSQIDRKGKSVNMT 206
            |:|...           ::..:||:...:::|...|      ...||    :::::...|:|.|.
plant   149 HMVHEG-----------RNRRMAVVTVLYKIGRADTFIRSLEKELEG----IAEMEEAEKNVGMI 198

  Fly   207 NP--LPLGEYISKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFRLLTANDDHLKN 269
            :|  :.:|.      ..|:.||||||||||::.|||........:|.||:...|:  |..|...:
plant   199 DPTKIKIGS------RKYYRYTGSLTTPPCTQNVTWSVVRKVRTVTRKQVKLLRV--AVHDDANS 255

  Fly   270 NFRPIQPLNDRTLY 283
            |.||:||.|.|.::
plant   256 NARPVQPTNKRIVH 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	28..281	CDD:215000	75/268 (28%)
ACA7	NP_172287.1	alpha_CA_prokaryotic_like	49..270	CDD:239398	74/263 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2610
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I2251
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm1014
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.820