DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH2 and ACA6

DIOPT Version :9

Sequence 1:	NP_648555.1	Gene:	CAH2 / 39390	FlyBaseID:	FBgn0027843	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_193832.1	Gene:	ACA6 / 827847	AraportID:	AT4G21000	Length:	260	Species:	Arabidopsis thaliana

Alignment Length:	273	Identity:	72/273 - (26%)
Similarity:	116/273 - (42%)	Gaps:	79/273 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FAIVIAPILICASLVLAQDFG------YEGR--HGPEHWSE---DYARCS-GKHQSPINI--DQV 59
            |..:.:|.::   .|.|::.|      |:.:  .||..|.:   .:..|| ||.||||::  ::|
plant    15 FIDLFSPNIL---FVYAREIGNKPLFTYKQKTEKGPAEWGKLDPQWKVCSTGKIQSPIDLTDERV 76

  Fly    60 SAV-EKKFPKLEFFNFKVVPDNLQMTNNGHTVLVKMSYNEDEIPSVRGGPLA-EKTPLGYQFEQF 122
            |.: ::...|    ::|  |.:..:.:.||.|:|  |:..|      ||.:. .:|  .|:..|.
plant    77 SLIHDQALSK----HYK--PASAVIQSRGHDVMV--SWKGD------GGKITIHQT--DYKLVQC 125

  Fly   123 HFHWGENDTIGSEDLINNRAYPAELHVVLRNLEYPDFASALDKDHGIAVMAFFFQVGDKSTGGYE 187
            |:|      ..||..||..:|..|||:|        ..||..|   ..|:...:::|:..    |
plant   126 HWH------SPSEHTINGTSYDLELHMV--------HTSASGK---TTVVGVLYKLGEPD----E 169

  Fly   188 GFTNLLSQIDRKGK---SVNMTNPLPLGEYISKSVESYFSYTGSLTTPPCSEEVTW--------- 240
            ..|.:|:.|...||   .:.:.:|    ..|.....:::.|.||||.|||:|.|.|
plant   170 FLTKILNGIKGVGKKEIDLGIVDP----RDIRFETNNFYRYIGSLTIPPCTEGVIWTVQKRVLYF 230

  Fly   241 -------IDFTTP 246
                   |.|.||
plant   231 FCFCYRLIIFVTP 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	28..281	CDD:215000	68/254 (27%)
ACA6	NP_193832.1	PLN02179	1..235	CDD:177835	68/263 (26%)
ACA6	NP_193832.1	alpha_CA_prokaryotic_like	46..225	CDD:239398	62/219 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2610
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I2251
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm1014
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.730