DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH2 and ACA4

DIOPT Version :9

Sequence 1:	NP_648555.1	Gene:	CAH2 / 39390	FlyBaseID:	FBgn0027843	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_193831.1	Gene:	ACA4 / 827846	AraportID:	AT4G20990	Length:	267	Species:	Arabidopsis thaliana

Alignment Length:	267	Identity:	76/267 - (28%)
Similarity:	119/267 - (44%)	Gaps:	52/267 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 FGYEGR--HGPEHWSE---DYARC-SGKHQSPINI--DQVSAVEKKFPKLEFFNFKVVPDNLQMT 84
            |.||.:  .|||.|.:   .:..| :|::||||::  ::||.:..     :.:..:..|....:|
plant    36 FTYEQKTEKGPEGWGKINPHWKVCNTGRYQSPIDLTNERVSLIHD-----QAWTRQYKPAPAVIT 95

  Fly    85 NNGHTVLVKMSYNEDEIPSVRGGPLAEKTPLGYQFEQFHFHWGENDTIGSEDLINNRAYPAELHV 149
            |.||.::|  |:..|     .|.....||  .:...|.|:|      ..||..:|...|..|||:
plant    96 NRGHDIMV--SWKGD-----AGKMTIRKT--DFNLVQCHWH------SPSEHTVNGTRYDLELHM 145

  Fly   150 VLRNLEYPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTNLLSQIDRKG-KSVN--MTNPLPL 211
            |        ..||..:   .||:...:::|:.:    |..|.||:.|...| |.:|  |.:|
plant   146 V--------HTSARGR---TAVIGVLYKLGEPN----EFLTKLLNGIKAVGNKEINLGMIDP--- 192

  Fly   212 GEYISKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFRLLTANDDHLKNNFRPIQP 276
             ..|......::.|.||||.|||:|.|.|........|:.:|:.|.|  .|.||..:.|.||:|.
plant   193 -REIRFQTRKFYRYIGSLTVPPCTEGVIWTVVKRVNTISMEQITALR--QAVDDGFETNSRPVQD 254

  Fly   277 LNDRTLY 283
            ...|:::
plant   255 SKGRSVW 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	28..281	CDD:215000	75/263 (29%)
ACA4	NP_193831.1	PLN02179	1..226	CDD:177835	64/228 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2610
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I2251
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	1	1.000	-	-		mtm1014
orthoMCL	1	0.900	-	-		OOG6_100138
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.820