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Protein Alignment CAH2 and CA12

DIOPT Version :9

Sequence 1:	NP_648555.1	Gene:	CAH2 / 39390	FlyBaseID:	FBgn0027843	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_001209.1	Gene:	CA12 / 771	HGNCID:	1371	Length:	354	Species:	Homo sapiens

Alignment Length:	324	Identity:	95/324 - (29%)
Similarity:	156/324 - (48%)	Gaps:	41/324 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 YEGRHGPEHWSEDYARCSGKHQSPINI-DQVSAVEKKFPKLEFFNFKVVPD-NLQMTNNGHTVLV 92
            |.|..|...||:.|..|.|..||||:: ..:...:.....|||..:.:..: ...:|||||:|.:
Human    34 YFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKL 98

  Fly    93 KMSYNEDEIPS---VRGGPLAEKTPLGYQFEQFHFHWGE-NDTIGSEDLINNRAYPAELHVVLRN 153
                   .:||   ::|  |..:    |...|.|.|||. ||..|||..::.:.:.||||:|..|
Human    99 -------NLPSDMHIQG--LQSR----YSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYN 150

  Fly   154 LE-YPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTNLLSQIDRKGKSVNMTNPLPLGEYISK 217
            .: |||.::|.:|..|:||:|...::|..:. .|:...:.|..:..||:...:.. ..:.|.:.:
Human   151 SDLYPDASTASNKSEGLAVLAVLIEMGSFNP-SYDKIFSHLQHVKYKGQEAFVPG-FNIEELLPE 213

  Fly   218 SVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFR---LLTANDD----HLKNNFRPIQ 275
            ....|:.|.||||||||:..|.|..|..|:.|:::||.|..   ..|..||    .:.||||.:|
Human   214 RTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQ 278

  Fly   276 PLNDRTLYKNYIEIPIHNMGSIPLVDAENAAGKWRAQAAAVLLPLVVLAALS-----RTSIFRG 334
            ..::|.:|.::.::.:.....:.|       |...:.|.|.:|.:.::..:|     |.||.:|
Human   279 KFDERLVYTSFSQVQVCTAAGLSL-------GIILSLALAGILGICIVVVVSIWLFRRKSIKKG 335

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.