Protein Alignment CAH2 and CA11

DIOPT Version :9

• Sequence 1: NP_648555.1
• Gene: CAH2 / 39390
• FlyBaseID: FBgn0027843
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_001208.2
• Gene: CA11 / 770
• HGNCID: 1370
• Length: 328
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 76/280 - (27%)
• Similarity: 126/280 - (45%)
• Gaps: 54/280 - (19%)

  Fly    35 GPEHW---SEDYARCS-GKHQSPINIDQVSAVEKKFPKLEFFNFKVVPDNLQMTNNGHTVLVKMS 95
            ||..|   :..::.|: ||.|||::::....:...|          :|. |:::..|..:...:
Human    48 GPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPF----------LPP-LRLSTGGEKLRGTL- 100

  Fly    96 YNEDE----------IPSVRGGPLAEKTPLGYQFEQFHFHWGENDTIGSEDLINNRAYPAELHVV 150
            ||...          :.:|.||||.    ..::..:....:|..|..|||..||::.:.||:.::
Human   101 YNTGRHVSFLPAPRPVVNVSGGPLL----YSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLI 161

  Fly   151 LRNLE-YPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTN--LLSQIDRKGK-------SVNM 205
            ..|.| |.:|::|....:|:|:::.|..|...|........|  .:::|..|..       |:.:
Human   162 HFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLEL 226

  Fly   206 TNPLPLGEYISKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFRLLTAND-----D 265
            ..|...|         :.:|.|||:||||||.||||.....::||..|:::.|||:.|.     .
Human   227 LFPESFG---------FITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQ 282

  Fly   266 HLKNNFRPIQPLNDRTLYKN 285
            .|..|.||:|||..|.|..|
Human   283 SLSGNSRPLQPLAHRALRGN 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	28..281	CDD:215000	73/274 (27%)
CA11	NP_001208.2	alpha_CARP_X_XI_like	48..304	CDD:239395	76/280 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..328		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820