Protein Alignment CAH2 and CA6

DIOPT Version :9

• Sequence 1: NP_648555.1
• Gene: CAH2 / 39390
• FlyBaseID: FBgn0027843
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: XP_011540386.1
• Gene: CA6 / 765
• HGNCID: 1380
• Length: 324
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 86/289 - (29%)
• Similarity: 142/289 - (49%)
• Gaps: 32/289 - (11%)

  Fly    16 ILICASLVL-------AQDFGY-EGRHGPEHWSEDYARCSGKHQSPINIDQVSAVEKKFPKLEFF 72
            :::..||.|       ..|:.| ||.....||.:.|..|.|:.|||||:.:...  :..|.|:..
Human     8 LVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKV--RYNPSLKGL 70

  Fly    73 N---FKVVPDNLQMTNNGHTVLVKMSYNEDEIPSVRGGPLAEKTPLGYQFEQFHFHWG--ENDTI 132
            |   ::.......|.||||||.:       .:||.....:|:.|.  |..:|.|||||  .::..
Human    71 NMTGYETQAGEFPMVNNGHTVQI-------SLPSTMRMTVADGTV--YIAQQMHFHWGGASSEIS 126

  Fly   133 GSEDLINNRAYPAELHVVLRNLEYPDFASALDKDHGIAVMAFFFQVGD-KSTGGYEGFTNLLSQI 196
            |||..::...:..|:|:|..|.:|..:..|.|...|:||:|.|.:|.: .....|..|.:.|:.|
Human   127 GSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANI 191

  Fly   197 DRKGKSVNMTNPLPLGEYISKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFRLLT 261
            ...|:...:|. |.:.:.:.::::.|::|.||||||||:|.|.|......:.::..|:  ::|..
Human   192 KYPGQRTTLTG-LDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQV--WKLEN 253

  Fly   262 ANDDH----LKNNFRPIQPLNDRTLYKNY 286
            :..||    :.|::|..||||.|.:..|:
Human   254 SLLDHRNKTIHNDYRRTQPLNHRVVESNF 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	28..281	CDD:215000	80/263 (30%)
CA6	XP_011540386.1	alpha_CA_VI	35..283	CDD:239399	79/262 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820