DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAH2 and CA5A

DIOPT Version :9

Sequence 1:	NP_648555.1	Gene:	CAH2 / 39390	FlyBaseID:	FBgn0027843	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	XP_011521611.1	Gene:	CA5A / 763	HGNCID:	1377	Length:	376	Species:	Homo sapiens

Alignment Length:	145	Identity:	47/145 - (32%)
Similarity:	75/145 - (51%)	Gaps:	13/145 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 WSEDYARCSGKHQSPINI---DQVSAVEKKFPKLEFFNFKVVPDNLQMTNNGHTVLVKMSYNEDE 100
            |:...:...|..||||||   |.|...:.|..::.:    .....|.:.|.|:...|:.. :..|
Human    52 WTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVSY----EAASCLYIWNTGYLFQVEFD-DATE 111

  Fly   101 IPSVRGGPLAEKTPLGYQFEQFHFHWGENDTIGSEDLINNRAYPAELHVVLRN-LEYPDFASALD 164
            ...:.||||...    |:.:|||||||..:..|||..::..|||||||:|..| ::|.::..|:.
Human   112 ASGISGGPLENH----YRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVV 172

  Fly   165 KDHGIAVMAFFFQVG 179
            .::|:||:..|.::|
Human   173 GENGLAVIGVFLKLG 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	28..281	CDD:215000	47/145 (32%)
CA5A	XP_011521611.1	alpha_CA	61..>212	CDD:294017	46/136 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0000047
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X57
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920