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Protein Alignment CAH2 and CA1

DIOPT Version :9

Sequence 1:	NP_648555.1	Gene:	CAH2 / 39390	FlyBaseID:	FBgn0027843	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_001122301.1	Gene:	CA1 / 759	HGNCID:	1368	Length:	261	Species:	Homo sapiens

Alignment Length:	267	Identity:	89/267 - (33%)
Similarity:	138/267 - (51%)	Gaps:	17/267 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 DFGYEGRHGPEHWSEDYARCSGKHQSPINIDQVSAVEKKFPKLEFFNFKVVPDNL-QMTNNGHTV 90
            |:||:.::|||.||:.|...:|.:|||::|.  ::..|....|:..:....|... ::.|.||:.
Human     5 DWGYDDKNGPEQWSKLYPIANGNNQSPVDIK--TSETKHDTSLKPISVSYNPATAKEIINVGHSF 67

  Fly    91 LVKMSYNEDEIPSVRGGPLAEKTPLGYQFEQFHFHWGENDTIGSEDLINNRAYPAELHVVLRN-L 154
            .|....| |....::|||.::    .|:..|||||||..:..|||..::...|.|||||...| .
Human    68 HVNFEDN-DNRSVLKGGPFSD----SYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSA 127

  Fly   155 EYPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTNLLSQIDRKGKSVNMTNPLPLGEYISKSV 219
            :|...|.|..|..|:||:....:||: :....:...:.|..|..|||....||..| ...:..|:
Human   128 KYSSLAEAASKADGLAVIGVLMKVGE-ANPKLQKVLDALQAIKTKGKRAPFTNFDP-STLLPSSL 190

  Fly   220 ESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFRLLTANDD-----HLKNNFRPIQPLND 279
            : :::|.||||.||..|.||||.....|.::.:||..||.|.:|.:     .:::|.||.|||..
Human   191 D-FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKG 254

  Fly   280 RTLYKNY 286
            ||:..::
Human   255 RTVRASF 261

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.