Protein Alignment CAH2 and CA10

DIOPT Version :9

• Sequence 1: NP_648555.1
• Gene: CAH2 / 39390
• FlyBaseID: FBgn0027843
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_001076002.1
• Gene: CA10 / 56934
• HGNCID: 1369
• Length: 328
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 75/276 - (27%)
• Similarity: 130/276 - (47%)
• Gaps: 48/276 - (17%)

  Fly    36 PEHW---SEDYARCS-GKHQSPINIDQVSAVEKKFPKLEFFNFKVVPDNLQ---------MTNNG 87
            |..|   :..:..|| ||.|||:||:....:...|         :.|..:.         |.|.|
Human    47 PSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPF---------LTPLRINTGGRKVSGTMYNTG 102

  Fly    88 HTVLVKMSYNEDEIPSVRGGPLAEKTPLGYQFEQFHFHWGENDTIGSEDLINNRAYPAELHVVLR 152
            ..|.:::  :::.:.::.|||:.    ..::.|:...|:|..|:.|||.|:|.:|:..|:.::..
Human   103 RHVSLRL--DKEHLVNISGGPMT----YSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHY 161

  Fly   153 NLE-YPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTN--LLSQIDRKG-----KSVNMTNPL 209
            |.| |.:...|....:|:.|::.|.:|.|.|........|  .:::|..|.     :.:|:
Human   162 NHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNI---- 222

  Fly   210 PLGEYISKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFRLLTANDD-----HLKN 269
               |.:.....|:.:|.||:|.|||.|..:||....|:.||..|:::.|||:.|..     .:.:
Human   223 ---EELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSD 284

  Fly   270 NFRPIQPLNDRTLYKN 285
            ||||:||||:|.:..|
Human   285 NFRPVQPLNNRCIRTN 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	28..281	CDD:215000	73/270 (27%)
CA10	NP_001076002.1	alpha_CARP_X_XI_like	46..302	CDD:239395	75/276 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820